Phytochemicals and their effective role in the treatment of diabetes mellitus: a short review

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3 Citations (Scopus)

Abstract

There is a global increase in the incidence of diabetes mellitus (DM). Hyperglycemia is one of the prevailing conditions which gives rise to various diabetic complications. The major complications include diabetic nephropathy, retinopathy, neuropathy, delayed wound healing, heart attack, peripheral vascular disturbances and diabetic ketoacidosis. Treatment of complications due to DM always poses a challenge to the attending clinician. Alongsideallopathic medicines, DM and its complications were reported to be effectively treated with various natural products. In the present review, we discuss the role of different phytochemicals which were reported to be beneficial in the treatment of hyperglycemic conditions in DM. Most medicinal plants contain micronutrients, amino acids and proteins, mucilages, essential oils, sterols and triterpenoids, saponins, carotenoids, alkaloids, flavonoids, phenolic acids, tannins, bitter principles and coumarins. We discuss the effective role of these phytochemicals with an emphasis on secondary metabolites which mimic the action of insulin, and highlight their importance as future antidiabetic agents.

Original languageEnglish
Pages (from-to)1-18
Number of pages18
JournalPhytochemistry Reviews
DOIs
Publication statusAccepted/In press - 11 May 2018

Fingerprint

Phytochemicals
diabetes mellitus
phytopharmaceuticals
Diabetes Mellitus
Diabetes Complications
Coumarins
Diabetic Ketoacidosis
Micronutrients
Tannins
Saponins
Diabetic Nephropathies
Diabetic Retinopathy
Sterols
Volatile Oils
Carotenoids
Medicinal Plants
hypoglycemic agents
diabetic nephropathy
Biological Products
Alkaloids

Keywords

  • Complications
  • Diabetes mellitus
  • Hyperglycemia
  • Phytochemicals
  • Treatment

ASJC Scopus subject areas

  • Biotechnology
  • Plant Science

Cite this

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