Periventricular haemorrhage in very low birth weight Malaysian neonates

N. Y. Boo, L. C. Ong, N. S. Lye, K. P. Wong, M. Mastura

    Research output: Contribution to journalArticle

    3 Citations (Scopus)

    Abstract

    A prospective study was carried out to determine the incidence, clinical presentation, early outcome, and risk factors associated with periventricular haemorrhage (PVH) in 88 (84 per cent) of the 105 consecutive very low birth weight (VLBW) (< 1500 g) Malaysian neonates born in the Maternity Hospital, Kuala Lumpur. Based on the cranial ultrasound findings, PVH was detected in 86 of the 88 neonates (98 per cent, 95 per cent confidence intervals: 95 to 101). Seventeen (20 per cent of them had grade I, 52 (61 per cent) had grade II, 7 (8 per cent) had grade III and 10 (12 per cent) had grade IV PVH. PVH was detected in all the affected neonates by the fifth day of life. Sixty-four neonates (74 per cent) were symptomatic when PVH was first detected. Shock (P<0.01), pallor (P=0.028), low haematocrit of less than 40 per cent (P<0.01), convulsion (P<0.001), and bulging of anterior fontanelle (P=0.019) were significantly more common in the neonates with severe PVH (grades III or IV). Death occurred in 43/86 (50 per cent, 95 per cent confidence interval: 39.61 per cent) of the neonates with PVH before their first discharge from the hospital. Ventriculomegaly developed in 29/43 (67 per cent, 95 per cent confidence intervals: 54.4-81.4) of the survivors with PVH. Our study suggests that PVH is a common problem in the Malaysian VLBW neonates. To reduce the incidence and severity of this condition, prevention of preterm delivery and improvement in the basic facilities for neonatal care would help.

    Original languageEnglish
    Pages (from-to)224-229
    Number of pages6
    JournalJournal of Tropical Pediatrics
    Volume39
    Issue number4
    Publication statusPublished - 1993

    Fingerprint

    Very Low Birth Weight Infant
    Confidence interval
    Newborn Infant
    Hemorrhage
    Incidence
    Ultrasonics
    Risk Factors
    Ultrasound
    Consecutive
    Shock
    Confidence Intervals
    Cranial Fontanelles
    Pallor
    Low birth weight
    Maternity Hospitals
    Hematocrit
    Seizures
    Prospective Studies

    ASJC Scopus subject areas

    • Immunology
    • Pediatrics, Perinatology, and Child Health
    • Public Health, Environmental and Occupational Health
    • Statistics, Probability and Uncertainty
    • Applied Mathematics
    • Genetics(clinical)
    • Biotechnology
    • Infectious Diseases

    Cite this

    Boo, N. Y., Ong, L. C., Lye, N. S., Wong, K. P., & Mastura, M. (1993). Periventricular haemorrhage in very low birth weight Malaysian neonates. Journal of Tropical Pediatrics, 39(4), 224-229.

    Periventricular haemorrhage in very low birth weight Malaysian neonates. / Boo, N. Y.; Ong, L. C.; Lye, N. S.; Wong, K. P.; Mastura, M.

    In: Journal of Tropical Pediatrics, Vol. 39, No. 4, 1993, p. 224-229.

    Research output: Contribution to journalArticle

    Boo, NY, Ong, LC, Lye, NS, Wong, KP & Mastura, M 1993, 'Periventricular haemorrhage in very low birth weight Malaysian neonates', Journal of Tropical Pediatrics, vol. 39, no. 4, pp. 224-229.
    Boo, N. Y. ; Ong, L. C. ; Lye, N. S. ; Wong, K. P. ; Mastura, M. / Periventricular haemorrhage in very low birth weight Malaysian neonates. In: Journal of Tropical Pediatrics. 1993 ; Vol. 39, No. 4. pp. 224-229.
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