Paraneoplastic neurological disorder in nasopharyngeal carcinoma

Research output: Contribution to journalArticle

Abstract

Paraneoplastic neurological disorder (PND) is a condition due to immune cross-reactivity between the tumour cells and the normal tissue, whereby the “onconeural” antibodies attack the normal host nervous system. It can present within weeks to months before or after the diagnosis of malignancies. Nasopharyngeal carcinoma is associated with paraneoplastic syndrome, for example, dermatomyositis, and rarely with a neurological disorder. We report on a case of nasopharyngeal carcinoma with probable PND. Otolaryngologists, oncologists and neurologists need to be aware of this condition in order to make an accurate diagnosis and to provide prompt treatment.

Original languageEnglish
Pages (from-to)113-116
Number of pages4
JournalMalaysian Journal of Medical Sciences
Volume24
Issue number1
DOIs
Publication statusPublished - 1 Jan 2017

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Nervous System Diseases
Paraneoplastic Syndromes
Dermatomyositis
Nervous System
Neoplasms
Antibodies
Nasopharyngeal carcinoma
Therapeutics

Keywords

  • Nasopharyngeal carcinoma
  • Nervous system
  • Neurological disorder
  • Paraneoplastic polyneuropathy
  • Paraneoplastic syndrome
  • PND

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Paraneoplastic neurological disorder in nasopharyngeal carcinoma. / Ng, Sze Yin; Kong, Min Han; Mohamad Yunus, Mohd. Razif.

In: Malaysian Journal of Medical Sciences, Vol. 24, No. 1, 01.01.2017, p. 113-116.

Research output: Contribution to journalArticle

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