Papuabalanols A and B, new tannins from Balanophora papuana

Takahiro Hosoya, Asami Nakata, Kazumasa Zaima, Jalifah Latip, Laily Bin Din, Noramly Muslim, Hiroshi Morita

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Two new dehydrohexahydroxydiphenoyl (DHHDP) esters of dihydrochalcone glycosides, papuabalanols A (1) and B (2) were isolated from the ethyl acetate extract of Balanophora papuana. Their structures were elucidated on the basis of spectroscopic data and chemical evidences. Papuabalanol A (1) showed moderate vasodilator effect on rat aorta and papuabalanol B (2) showed potent inhibition of mushroom tyrosinase and anti-melanogenesis in B16 mouse melanoma cells.

Original languageEnglish
Pages (from-to)738-741
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume58
Issue number5
DOIs
Publication statusPublished - May 2010

Fingerprint

Tannins
Experimental Melanomas
Monophenol Monooxygenase
Agaricales
Glycosides
Vasodilator Agents
Aorta
Rats
Esters
papuabalanol A
papuabalanol B
ethyl acetate
dihydrochalcone

Keywords

  • Anti-melanogenesis
  • Balanophora papuana
  • Dehydroellagitannin
  • Papuabalanol
  • Tyrosinase inhibitory activity
  • Vasodilator

ASJC Scopus subject areas

  • Drug Discovery
  • Chemistry(all)

Cite this

Hosoya, T., Nakata, A., Zaima, K., Latip, J., Din, L. B., Muslim, N., & Morita, H. (2010). Papuabalanols A and B, new tannins from Balanophora papuana. Chemical and Pharmaceutical Bulletin, 58(5), 738-741. https://doi.org/10.1248/cpb.58.738

Papuabalanols A and B, new tannins from Balanophora papuana. / Hosoya, Takahiro; Nakata, Asami; Zaima, Kazumasa; Latip, Jalifah; Din, Laily Bin; Muslim, Noramly; Morita, Hiroshi.

In: Chemical and Pharmaceutical Bulletin, Vol. 58, No. 5, 05.2010, p. 738-741.

Research output: Contribution to journalArticle

Hosoya, T, Nakata, A, Zaima, K, Latip, J, Din, LB, Muslim, N & Morita, H 2010, 'Papuabalanols A and B, new tannins from Balanophora papuana', Chemical and Pharmaceutical Bulletin, vol. 58, no. 5, pp. 738-741. https://doi.org/10.1248/cpb.58.738
Hosoya, Takahiro ; Nakata, Asami ; Zaima, Kazumasa ; Latip, Jalifah ; Din, Laily Bin ; Muslim, Noramly ; Morita, Hiroshi. / Papuabalanols A and B, new tannins from Balanophora papuana. In: Chemical and Pharmaceutical Bulletin. 2010 ; Vol. 58, No. 5. pp. 738-741.
@article{e3fbd549d2f943f29a73734c1b679a2d,
title = "Papuabalanols A and B, new tannins from Balanophora papuana",
abstract = "Two new dehydrohexahydroxydiphenoyl (DHHDP) esters of dihydrochalcone glycosides, papuabalanols A (1) and B (2) were isolated from the ethyl acetate extract of Balanophora papuana. Their structures were elucidated on the basis of spectroscopic data and chemical evidences. Papuabalanol A (1) showed moderate vasodilator effect on rat aorta and papuabalanol B (2) showed potent inhibition of mushroom tyrosinase and anti-melanogenesis in B16 mouse melanoma cells.",
keywords = "Anti-melanogenesis, Balanophora papuana, Dehydroellagitannin, Papuabalanol, Tyrosinase inhibitory activity, Vasodilator",
author = "Takahiro Hosoya and Asami Nakata and Kazumasa Zaima and Jalifah Latip and Din, {Laily Bin} and Noramly Muslim and Hiroshi Morita",
year = "2010",
month = "5",
doi = "10.1248/cpb.58.738",
language = "English",
volume = "58",
pages = "738--741",
journal = "Chemical and Pharmaceutical Bulletin",
issn = "0009-2363",
publisher = "Pharmaceutical Society of Japan",
number = "5",

}

TY - JOUR

T1 - Papuabalanols A and B, new tannins from Balanophora papuana

AU - Hosoya, Takahiro

AU - Nakata, Asami

AU - Zaima, Kazumasa

AU - Latip, Jalifah

AU - Din, Laily Bin

AU - Muslim, Noramly

AU - Morita, Hiroshi

PY - 2010/5

Y1 - 2010/5

N2 - Two new dehydrohexahydroxydiphenoyl (DHHDP) esters of dihydrochalcone glycosides, papuabalanols A (1) and B (2) were isolated from the ethyl acetate extract of Balanophora papuana. Their structures were elucidated on the basis of spectroscopic data and chemical evidences. Papuabalanol A (1) showed moderate vasodilator effect on rat aorta and papuabalanol B (2) showed potent inhibition of mushroom tyrosinase and anti-melanogenesis in B16 mouse melanoma cells.

AB - Two new dehydrohexahydroxydiphenoyl (DHHDP) esters of dihydrochalcone glycosides, papuabalanols A (1) and B (2) were isolated from the ethyl acetate extract of Balanophora papuana. Their structures were elucidated on the basis of spectroscopic data and chemical evidences. Papuabalanol A (1) showed moderate vasodilator effect on rat aorta and papuabalanol B (2) showed potent inhibition of mushroom tyrosinase and anti-melanogenesis in B16 mouse melanoma cells.

KW - Anti-melanogenesis

KW - Balanophora papuana

KW - Dehydroellagitannin

KW - Papuabalanol

KW - Tyrosinase inhibitory activity

KW - Vasodilator

UR - http://www.scopus.com/inward/record.url?scp=77951700394&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77951700394&partnerID=8YFLogxK

U2 - 10.1248/cpb.58.738

DO - 10.1248/cpb.58.738

M3 - Article

C2 - 20460807

AN - SCOPUS:77951700394

VL - 58

SP - 738

EP - 741

JO - Chemical and Pharmaceutical Bulletin

JF - Chemical and Pharmaceutical Bulletin

SN - 0009-2363

IS - 5

ER -