Palm vitamin E improves bone metabolism and survival rate in thyrotoxic rats

Ima Nirwana Soelaiman, A. Kiftiah, T. Sariza, M. T Abd Gapor, B. A K Khalid

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

The effects of vitamin E derived from palm oil on bone turnover in thyrotoxic rats were studied. Palm vitamin E reduced bone resorption to a greater extent than bone formation in thyrotoxic rats, suggesting a net reduction in bone loss. The action of palm vitamin E is probably due to its antioxidant properties. Survival rates were also significantly increased in thyrotoxic rats given palm vitamin E, suggesting the role of free radicals in the overall morbidity and mortality in thyrotoxicosis. Copyright (C) 1999 Elsevier Science Inc.

Original languageEnglish
Pages (from-to)621-626
Number of pages6
JournalGeneral Pharmacology
Volume32
Issue number5
DOIs
Publication statusPublished - May 1999

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Vitamin E
Survival Rate
Bone and Bones
Thyrotoxicosis
Bone Remodeling
Bone Resorption
Osteogenesis
Free Radicals
Antioxidants
Morbidity
Mortality

Keywords

  • Bone metabolism
  • Male rats
  • Palm vitamin E
  • Thyrotoxicosis

ASJC Scopus subject areas

  • Pharmacology

Cite this

Palm vitamin E improves bone metabolism and survival rate in thyrotoxic rats. / Soelaiman, Ima Nirwana; Kiftiah, A.; Sariza, T.; Gapor, M. T Abd; Khalid, B. A K.

In: General Pharmacology, Vol. 32, No. 5, 05.1999, p. 621-626.

Research output: Contribution to journalArticle

Soelaiman, Ima Nirwana ; Kiftiah, A. ; Sariza, T. ; Gapor, M. T Abd ; Khalid, B. A K. / Palm vitamin E improves bone metabolism and survival rate in thyrotoxic rats. In: General Pharmacology. 1999 ; Vol. 32, No. 5. pp. 621-626.
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