Palm kernel oil-based polyester polyurethane composites incorporated with multi-walled carbon nanotubes for biomedical application

Nurul Nabilah bt Zulkifli, Khairiah Badri, Khairul Anuar Mat Amin

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: In this study, polyurethane (PU) films from palm kernel oil-based polyester (PKO-p) incorporated multi-walled carbon nanotubes (MWNTs) were prepared via evaporative casting method. Nanoparticle fluid dispersions containing 0.01, 0.04 and 0.08 % wt. of MWNTs were added into PKO-p-based resin and mixed by digital probe sonicator for 20 min followed by mixing with isocyanate to produce PU-MWNTs composite films. The mechanical properties, water resistance, water vapor transmission rates (WVTR), biocompatibility, and antibacterial activities of the PU-MWNTs composite films were examined. Results: Results show that PU containing 0.01 wt. % of MWNTs demonstrated optimum mechanical properties as it possessed high tensile strength, modulus, and good flexibility compared to PU film and other PU-MWNTs composite films. There are no significant difference in swelling values as well as water vapor transmission rates for PU film and PU-MWNTs composite films. All the films showed low swelling values (17–23 %) and WVTR values in the range 181–269 g m−2 d−1. Cell studies revealed that PU and PU-MWNTs composite films are non-cytotoxic to human skin fibroblast cells (CRL2522) and the cell proliferation was increased after incubation of 72 h. The in vitro qualitative antibacterial results showed both PU and PU-MWNTs composite films exhibited bactericidal effect against Gram-positive (Staphylococcus aureus and Bacillus cereus) and Gram-negative bacteria (Escherichia coli and Klebsiella pneumonia). Conclusions: In summary, incorporation of MWNTs improved the mechanical properties of the polyurethane films with no cytotoxic effect against normal human skin fibroblast cells. [Figure not available: see fulltext. Caption: Fluorescence microscope images of the cell viability of normal human skin fibroblast cells (CRL2522, ATCC) which changed their morphology to elongated/spindle-like shape after being cultured for 72 h on polyurethane (PU) film, PU-MWNT01, PU-MWNT04, and PU-MWNT08 composite films.].

Original languageEnglish
Article number25
JournalBioresources and Bioprocessing
Volume3
Issue number1
DOIs
Publication statusPublished - 1 Dec 2016

Fingerprint

palm kernel oil
carbon nanotubes
Carbon Nanotubes
polyurethanes
Polyesters
Palm oil
Polyurethanes
composite materials
polyesters
Carbon nanotubes
films (materials)
Composite materials
Composite films
Steam
Fibroblasts
water vapor
Cells
skin (animal)
Water vapor
mechanical properties

Keywords

  • Antibacterial activities
  • Biocompatibility
  • Composites
  • MWNTs
  • Palm kernel oil-based polyester
  • Polyurethane

ASJC Scopus subject areas

  • Biotechnology
  • Food Science
  • Biomedical Engineering
  • Renewable Energy, Sustainability and the Environment

Cite this

Palm kernel oil-based polyester polyurethane composites incorporated with multi-walled carbon nanotubes for biomedical application. / Zulkifli, Nurul Nabilah bt; Badri, Khairiah; Amin, Khairul Anuar Mat.

In: Bioresources and Bioprocessing, Vol. 3, No. 1, 25, 01.12.2016.

Research output: Contribution to journalArticle

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abstract = "Background: In this study, polyurethane (PU) films from palm kernel oil-based polyester (PKO-p) incorporated multi-walled carbon nanotubes (MWNTs) were prepared via evaporative casting method. Nanoparticle fluid dispersions containing 0.01, 0.04 and 0.08 {\%} wt. of MWNTs were added into PKO-p-based resin and mixed by digital probe sonicator for 20 min followed by mixing with isocyanate to produce PU-MWNTs composite films. The mechanical properties, water resistance, water vapor transmission rates (WVTR), biocompatibility, and antibacterial activities of the PU-MWNTs composite films were examined. Results: Results show that PU containing 0.01 wt. {\%} of MWNTs demonstrated optimum mechanical properties as it possessed high tensile strength, modulus, and good flexibility compared to PU film and other PU-MWNTs composite films. There are no significant difference in swelling values as well as water vapor transmission rates for PU film and PU-MWNTs composite films. All the films showed low swelling values (17–23 {\%}) and WVTR values in the range 181–269 g m−2 d−1. Cell studies revealed that PU and PU-MWNTs composite films are non-cytotoxic to human skin fibroblast cells (CRL2522) and the cell proliferation was increased after incubation of 72 h. The in vitro qualitative antibacterial results showed both PU and PU-MWNTs composite films exhibited bactericidal effect against Gram-positive (Staphylococcus aureus and Bacillus cereus) and Gram-negative bacteria (Escherichia coli and Klebsiella pneumonia). Conclusions: In summary, incorporation of MWNTs improved the mechanical properties of the polyurethane films with no cytotoxic effect against normal human skin fibroblast cells. [Figure not available: see fulltext. Caption: Fluorescence microscope images of the cell viability of normal human skin fibroblast cells (CRL2522, ATCC) which changed their morphology to elongated/spindle-like shape after being cultured for 72 h on polyurethane (PU) film, PU-MWNT01, PU-MWNT04, and PU-MWNT08 composite films.].",
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N2 - Background: In this study, polyurethane (PU) films from palm kernel oil-based polyester (PKO-p) incorporated multi-walled carbon nanotubes (MWNTs) were prepared via evaporative casting method. Nanoparticle fluid dispersions containing 0.01, 0.04 and 0.08 % wt. of MWNTs were added into PKO-p-based resin and mixed by digital probe sonicator for 20 min followed by mixing with isocyanate to produce PU-MWNTs composite films. The mechanical properties, water resistance, water vapor transmission rates (WVTR), biocompatibility, and antibacterial activities of the PU-MWNTs composite films were examined. Results: Results show that PU containing 0.01 wt. % of MWNTs demonstrated optimum mechanical properties as it possessed high tensile strength, modulus, and good flexibility compared to PU film and other PU-MWNTs composite films. There are no significant difference in swelling values as well as water vapor transmission rates for PU film and PU-MWNTs composite films. All the films showed low swelling values (17–23 %) and WVTR values in the range 181–269 g m−2 d−1. Cell studies revealed that PU and PU-MWNTs composite films are non-cytotoxic to human skin fibroblast cells (CRL2522) and the cell proliferation was increased after incubation of 72 h. The in vitro qualitative antibacterial results showed both PU and PU-MWNTs composite films exhibited bactericidal effect against Gram-positive (Staphylococcus aureus and Bacillus cereus) and Gram-negative bacteria (Escherichia coli and Klebsiella pneumonia). Conclusions: In summary, incorporation of MWNTs improved the mechanical properties of the polyurethane films with no cytotoxic effect against normal human skin fibroblast cells. [Figure not available: see fulltext. Caption: Fluorescence microscope images of the cell viability of normal human skin fibroblast cells (CRL2522, ATCC) which changed their morphology to elongated/spindle-like shape after being cultured for 72 h on polyurethane (PU) film, PU-MWNT01, PU-MWNT04, and PU-MWNT08 composite films.].

AB - Background: In this study, polyurethane (PU) films from palm kernel oil-based polyester (PKO-p) incorporated multi-walled carbon nanotubes (MWNTs) were prepared via evaporative casting method. Nanoparticle fluid dispersions containing 0.01, 0.04 and 0.08 % wt. of MWNTs were added into PKO-p-based resin and mixed by digital probe sonicator for 20 min followed by mixing with isocyanate to produce PU-MWNTs composite films. The mechanical properties, water resistance, water vapor transmission rates (WVTR), biocompatibility, and antibacterial activities of the PU-MWNTs composite films were examined. Results: Results show that PU containing 0.01 wt. % of MWNTs demonstrated optimum mechanical properties as it possessed high tensile strength, modulus, and good flexibility compared to PU film and other PU-MWNTs composite films. There are no significant difference in swelling values as well as water vapor transmission rates for PU film and PU-MWNTs composite films. All the films showed low swelling values (17–23 %) and WVTR values in the range 181–269 g m−2 d−1. Cell studies revealed that PU and PU-MWNTs composite films are non-cytotoxic to human skin fibroblast cells (CRL2522) and the cell proliferation was increased after incubation of 72 h. The in vitro qualitative antibacterial results showed both PU and PU-MWNTs composite films exhibited bactericidal effect against Gram-positive (Staphylococcus aureus and Bacillus cereus) and Gram-negative bacteria (Escherichia coli and Klebsiella pneumonia). Conclusions: In summary, incorporation of MWNTs improved the mechanical properties of the polyurethane films with no cytotoxic effect against normal human skin fibroblast cells. [Figure not available: see fulltext. Caption: Fluorescence microscope images of the cell viability of normal human skin fibroblast cells (CRL2522, ATCC) which changed their morphology to elongated/spindle-like shape after being cultured for 72 h on polyurethane (PU) film, PU-MWNT01, PU-MWNT04, and PU-MWNT08 composite films.].

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