Painful Oral Ulcers with Hydroxyurea Therapy

M. R. Norhaya, S. K. Cheong, O. Ainoon, Noor Hamidah Hussin

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Five patients treated with hydroxyurea for various haematological malignancies developed multiple painful oral ulcers. Their neutrophil counts were either normal or elevated. The ulcers disappeared with cessation of hydroxyurea. Oral ulcers recurred when hydroxyurea was resumed in one of the patients. As the patients were unable to tolerate this painful side effect, hydroxyurea had to be discontinued. Appearance of painful oral ulceration seems to be independent of dosing rate or total cumulative dose of hydroxyurea.

Original languageEnglish
Pages (from-to)283-284
Number of pages2
JournalSingapore Medical Journal
Volume38
Issue number7
Publication statusPublished - Jul 1997

Fingerprint

Oral Ulcer
Hydroxyurea
Therapeutics
Hematologic Neoplasms
Ulcer
Neutrophils

Keywords

  • Adverse effect
  • Chronic myeloid leukaemia
  • Essential thrombocythaemia
  • Polycythaemia

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Norhaya, M. R., Cheong, S. K., Ainoon, O., & Hussin, N. H. (1997). Painful Oral Ulcers with Hydroxyurea Therapy. Singapore Medical Journal, 38(7), 283-284.

Painful Oral Ulcers with Hydroxyurea Therapy. / Norhaya, M. R.; Cheong, S. K.; Ainoon, O.; Hussin, Noor Hamidah.

In: Singapore Medical Journal, Vol. 38, No. 7, 07.1997, p. 283-284.

Research output: Contribution to journalArticle

Norhaya, MR, Cheong, SK, Ainoon, O & Hussin, NH 1997, 'Painful Oral Ulcers with Hydroxyurea Therapy', Singapore Medical Journal, vol. 38, no. 7, pp. 283-284.
Norhaya MR, Cheong SK, Ainoon O, Hussin NH. Painful Oral Ulcers with Hydroxyurea Therapy. Singapore Medical Journal. 1997 Jul;38(7):283-284.
Norhaya, M. R. ; Cheong, S. K. ; Ainoon, O. ; Hussin, Noor Hamidah. / Painful Oral Ulcers with Hydroxyurea Therapy. In: Singapore Medical Journal. 1997 ; Vol. 38, No. 7. pp. 283-284.
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