Outbreak detection model based on danger theory

Mohamad Farhan Mohamad Mohsin, Azuraliza Abu Bakar, Abdul Razak Hamdan

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

In outbreak detection, one of the key issues is the need to deal with the weakness of early outbreak signals because this causes the detection model to have has less capability in terms of robustness when unseen outbreak patterns vary from those in the trained model. As a result, an imbalance between high detection rate and low false alarm rate occurs. To solve this problem, this study proposes a novel outbreak detection model based on danger theory; a bio-inspired method that replicates how the human body fights pathogens. We propose a signal formalization approach based on cumulative sum and a cumulative mature antigen contact value to suit the outbreak characteristic and danger theory. Two outbreak diseases, dengue and SARS, are subjected to a danger theory algorithm; namely the dendritic cell algorithm. To evaluate the model, four measurement metrics are applied: detection rate, specificity, false alarm rate, and accuracy. From the experiment, the proposed model outperforms the other detection approaches and shows a significant improvement for both diseases outbreak detection. The findings reveal that the robustness of the proposed immune model increases when dealing with inconsistent outbreak signals. The model is able to detect new unknown outbreak patterns and can discriminate between outbreak and non-outbreak cases with a consistent high detection rate, high sensitivity, and lower false alarm rate even without a training phase.

Original languageEnglish
Pages (from-to)612-622
Number of pages11
JournalApplied Soft Computing Journal
Volume24
DOIs
Publication statusPublished - 2014

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Pathogens
Antigens
Experiments
Dendritic Cells

Keywords

  • Artificial immune system
  • Danger theory
  • Dendritic cell algorithm
  • Outbreak detection

ASJC Scopus subject areas

  • Software

Cite this

Outbreak detection model based on danger theory. / Mohamad Mohsin, Mohamad Farhan; Abu Bakar, Azuraliza; Hamdan, Abdul Razak.

In: Applied Soft Computing Journal, Vol. 24, 2014, p. 612-622.

Research output: Contribution to journalArticle

Mohamad Mohsin, Mohamad Farhan ; Abu Bakar, Azuraliza ; Hamdan, Abdul Razak. / Outbreak detection model based on danger theory. In: Applied Soft Computing Journal. 2014 ; Vol. 24. pp. 612-622.
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