Orthodontic treatment effects on inflammatory marker profiles in saliva before and after 2 archwire changes

Zulham Yamamoto, Ikmal Mohamad Jaafar, Rohaya Megat Abdul Wahab, Intan Zarin Zainol Abidin, Sahidan Senafi, Zaidah Zainal Ariffin, Shahrul Hisham Zainal Ariffin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Periodontal tissue changes exerted by external forces in orthodontic treatment allow tooth movement. The changes in periodontal tissues i.e. inflammation can be monitored using gingival crevicular fluid (GCF). GCF is a component of saliva. Saliva could be used to monitor periodontal disease progression. The use of saliva to monitor periodontal tissues changes during orthodontic treatment is still unknown. Therefore, we observed the profiles of inflammatory markers namely creatine kinase (CK), nitric oxide (NO), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) in saliva of orthodontic patients to evaluate their importance in orthodontic treatment. A total of 21 subjects (13 female and 8 male) participated in this study. Samples were collected from gingival crevicular fluid at three period of archwire changes: baseline (M0), 2 weeks after 0.014" NiTi archwire (M1), and 2 weeks after 0.018" NiTi archwire (M2). All enzyme activities i.e. CK, LDH and AST were measured spectrophotometrically at 340 nm. Griess assay was used to measure nitric oxide level. CK activity, NO level, LDH activity and AST activity in saliva samples did not show significant differences among period of archwire changes. The use of inflammatory marker profiles in saliva may not represent the changes in periodontal tissues during orthodontic treatment.

Original languageEnglish
Title of host publicationAIP Conference Proceedings
Pages208-214
Number of pages7
Volume1571
DOIs
Publication statusPublished - 2013
Event2013 UKM Faculty of Science and Technology Post-Graduate Colloquium - Selangor
Duration: 3 Jul 20134 Jul 2013

Other

Other2013 UKM Faculty of Science and Technology Post-Graduate Colloquium
CitySelangor
Period3/7/134/7/13

Fingerprint

saliva
markers
creatine
aspartates
lactates
dehydrogenases
nitric oxide
profiles
fluids
enzyme activity
teeth
progressions

Keywords

  • Aspartate aminotransferase
  • Creatine kinase
  • Inflammatory markers
  • Lactate dehydrogenase
  • Nitric oxide
  • Orthodontic

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Yamamoto, Z., Jaafar, I. M., Megat Abdul Wahab, R., Abidin, I. Z. Z., Senafi, S., Ariffin, Z. Z., & Zainal Ariffin, S. H. (2013). Orthodontic treatment effects on inflammatory marker profiles in saliva before and after 2 archwire changes. In AIP Conference Proceedings (Vol. 1571, pp. 208-214) https://doi.org/10.1063/1.4858656

Orthodontic treatment effects on inflammatory marker profiles in saliva before and after 2 archwire changes. / Yamamoto, Zulham; Jaafar, Ikmal Mohamad; Megat Abdul Wahab, Rohaya; Abidin, Intan Zarin Zainol; Senafi, Sahidan; Ariffin, Zaidah Zainal; Zainal Ariffin, Shahrul Hisham.

AIP Conference Proceedings. Vol. 1571 2013. p. 208-214.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Yamamoto, Z, Jaafar, IM, Megat Abdul Wahab, R, Abidin, IZZ, Senafi, S, Ariffin, ZZ & Zainal Ariffin, SH 2013, Orthodontic treatment effects on inflammatory marker profiles in saliva before and after 2 archwire changes. in AIP Conference Proceedings. vol. 1571, pp. 208-214, 2013 UKM Faculty of Science and Technology Post-Graduate Colloquium, Selangor, 3/7/13. https://doi.org/10.1063/1.4858656
Yamamoto Z, Jaafar IM, Megat Abdul Wahab R, Abidin IZZ, Senafi S, Ariffin ZZ et al. Orthodontic treatment effects on inflammatory marker profiles in saliva before and after 2 archwire changes. In AIP Conference Proceedings. Vol. 1571. 2013. p. 208-214 https://doi.org/10.1063/1.4858656
Yamamoto, Zulham ; Jaafar, Ikmal Mohamad ; Megat Abdul Wahab, Rohaya ; Abidin, Intan Zarin Zainol ; Senafi, Sahidan ; Ariffin, Zaidah Zainal ; Zainal Ariffin, Shahrul Hisham. / Orthodontic treatment effects on inflammatory marker profiles in saliva before and after 2 archwire changes. AIP Conference Proceedings. Vol. 1571 2013. pp. 208-214
@inproceedings{082267e3bb394fe5a7c524cb96cf6de3,
title = "Orthodontic treatment effects on inflammatory marker profiles in saliva before and after 2 archwire changes",
abstract = "Periodontal tissue changes exerted by external forces in orthodontic treatment allow tooth movement. The changes in periodontal tissues i.e. inflammation can be monitored using gingival crevicular fluid (GCF). GCF is a component of saliva. Saliva could be used to monitor periodontal disease progression. The use of saliva to monitor periodontal tissues changes during orthodontic treatment is still unknown. Therefore, we observed the profiles of inflammatory markers namely creatine kinase (CK), nitric oxide (NO), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) in saliva of orthodontic patients to evaluate their importance in orthodontic treatment. A total of 21 subjects (13 female and 8 male) participated in this study. Samples were collected from gingival crevicular fluid at three period of archwire changes: baseline (M0), 2 weeks after 0.014{"} NiTi archwire (M1), and 2 weeks after 0.018{"} NiTi archwire (M2). All enzyme activities i.e. CK, LDH and AST were measured spectrophotometrically at 340 nm. Griess assay was used to measure nitric oxide level. CK activity, NO level, LDH activity and AST activity in saliva samples did not show significant differences among period of archwire changes. The use of inflammatory marker profiles in saliva may not represent the changes in periodontal tissues during orthodontic treatment.",
keywords = "Aspartate aminotransferase, Creatine kinase, Inflammatory markers, Lactate dehydrogenase, Nitric oxide, Orthodontic",
author = "Zulham Yamamoto and Jaafar, {Ikmal Mohamad} and {Megat Abdul Wahab}, Rohaya and Abidin, {Intan Zarin Zainol} and Sahidan Senafi and Ariffin, {Zaidah Zainal} and {Zainal Ariffin}, {Shahrul Hisham}",
year = "2013",
doi = "10.1063/1.4858656",
language = "English",
isbn = "9780735411999",
volume = "1571",
pages = "208--214",
booktitle = "AIP Conference Proceedings",

}

TY - GEN

T1 - Orthodontic treatment effects on inflammatory marker profiles in saliva before and after 2 archwire changes

AU - Yamamoto, Zulham

AU - Jaafar, Ikmal Mohamad

AU - Megat Abdul Wahab, Rohaya

AU - Abidin, Intan Zarin Zainol

AU - Senafi, Sahidan

AU - Ariffin, Zaidah Zainal

AU - Zainal Ariffin, Shahrul Hisham

PY - 2013

Y1 - 2013

N2 - Periodontal tissue changes exerted by external forces in orthodontic treatment allow tooth movement. The changes in periodontal tissues i.e. inflammation can be monitored using gingival crevicular fluid (GCF). GCF is a component of saliva. Saliva could be used to monitor periodontal disease progression. The use of saliva to monitor periodontal tissues changes during orthodontic treatment is still unknown. Therefore, we observed the profiles of inflammatory markers namely creatine kinase (CK), nitric oxide (NO), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) in saliva of orthodontic patients to evaluate their importance in orthodontic treatment. A total of 21 subjects (13 female and 8 male) participated in this study. Samples were collected from gingival crevicular fluid at three period of archwire changes: baseline (M0), 2 weeks after 0.014" NiTi archwire (M1), and 2 weeks after 0.018" NiTi archwire (M2). All enzyme activities i.e. CK, LDH and AST were measured spectrophotometrically at 340 nm. Griess assay was used to measure nitric oxide level. CK activity, NO level, LDH activity and AST activity in saliva samples did not show significant differences among period of archwire changes. The use of inflammatory marker profiles in saliva may not represent the changes in periodontal tissues during orthodontic treatment.

AB - Periodontal tissue changes exerted by external forces in orthodontic treatment allow tooth movement. The changes in periodontal tissues i.e. inflammation can be monitored using gingival crevicular fluid (GCF). GCF is a component of saliva. Saliva could be used to monitor periodontal disease progression. The use of saliva to monitor periodontal tissues changes during orthodontic treatment is still unknown. Therefore, we observed the profiles of inflammatory markers namely creatine kinase (CK), nitric oxide (NO), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) in saliva of orthodontic patients to evaluate their importance in orthodontic treatment. A total of 21 subjects (13 female and 8 male) participated in this study. Samples were collected from gingival crevicular fluid at three period of archwire changes: baseline (M0), 2 weeks after 0.014" NiTi archwire (M1), and 2 weeks after 0.018" NiTi archwire (M2). All enzyme activities i.e. CK, LDH and AST were measured spectrophotometrically at 340 nm. Griess assay was used to measure nitric oxide level. CK activity, NO level, LDH activity and AST activity in saliva samples did not show significant differences among period of archwire changes. The use of inflammatory marker profiles in saliva may not represent the changes in periodontal tissues during orthodontic treatment.

KW - Aspartate aminotransferase

KW - Creatine kinase

KW - Inflammatory markers

KW - Lactate dehydrogenase

KW - Nitric oxide

KW - Orthodontic

UR - http://www.scopus.com/inward/record.url?scp=84897783419&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84897783419&partnerID=8YFLogxK

U2 - 10.1063/1.4858656

DO - 10.1063/1.4858656

M3 - Conference contribution

AN - SCOPUS:84897783419

SN - 9780735411999

VL - 1571

SP - 208

EP - 214

BT - AIP Conference Proceedings

ER -