Optimization of extraction procedure for determination of caffeine residue in water

Wan Mohd Afiq Wan Mohd Khalik, Md. Pauzi Abdullah, Fatinah Khafizah Baharudin, Siti Aminah Zulkepli

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Extraction procedure for determination of caffeine in water with aided experimental design was successfully optimized. Three variables, namely pH sample, flow rate and elution volume were tested during this study using 23 full factorial of central composite design. An optimum working condition was suggested at pH sample (6.4), flow rate (1.2 ml/min) and elution volume of caffeine from sorbent is 9.5 ml of methanol. Detection and quantification limits were obtained at 0.02 and 0.25 ng/ml respectively. Good recovery was calculated within the range of 80.9 - 93.7 % at three levels of concentration. Repeatability and reproducibility value show this method to be reliable for routine analysis with low RSD <10 %. Concentration levels of caffeine in real samples were recorded in the range of 0.64 - 59.01 ng/ml. Hierarchical cluster analysis grouped all stations into three clusters at Dlink/Dmax x 100 <15. Wastewater discharge from cafeteria or residential area was a solid reason linked to the presence of high caffeine during this study.

Original languageEnglish
Pages (from-to)720-728
Number of pages9
JournalJournal of Materials and Environmental Science
Volume7
Issue number3
Publication statusPublished - 2016

Fingerprint

Caffeine
Water
working conditions
experimental design
methanol
cluster analysis
Flow rate
wastewater
water
Cluster analysis
Sorbents
Design of experiments
Methanol
Wastewater
Recovery
rate
Composite materials
method
residential area
station

Keywords

  • Experimental design
  • Freshwater
  • Physcoactive drug
  • Response surface
  • Stimulant

ASJC Scopus subject areas

  • Environmental Chemistry
  • Pollution
  • Waste Management and Disposal
  • Materials Chemistry

Cite this

Khalik, W. M. A. W. M., Abdullah, M. P., Baharudin, F. K., & Zulkepli, S. A. (2016). Optimization of extraction procedure for determination of caffeine residue in water. Journal of Materials and Environmental Science, 7(3), 720-728.

Optimization of extraction procedure for determination of caffeine residue in water. / Khalik, Wan Mohd Afiq Wan Mohd; Abdullah, Md. Pauzi; Baharudin, Fatinah Khafizah; Zulkepli, Siti Aminah.

In: Journal of Materials and Environmental Science, Vol. 7, No. 3, 2016, p. 720-728.

Research output: Contribution to journalArticle

Khalik, WMAWM, Abdullah, MP, Baharudin, FK & Zulkepli, SA 2016, 'Optimization of extraction procedure for determination of caffeine residue in water', Journal of Materials and Environmental Science, vol. 7, no. 3, pp. 720-728.
Khalik, Wan Mohd Afiq Wan Mohd ; Abdullah, Md. Pauzi ; Baharudin, Fatinah Khafizah ; Zulkepli, Siti Aminah. / Optimization of extraction procedure for determination of caffeine residue in water. In: Journal of Materials and Environmental Science. 2016 ; Vol. 7, No. 3. pp. 720-728.
@article{684e70a10f3c47ae80302100c63ac99d,
title = "Optimization of extraction procedure for determination of caffeine residue in water",
abstract = "Extraction procedure for determination of caffeine in water with aided experimental design was successfully optimized. Three variables, namely pH sample, flow rate and elution volume were tested during this study using 23 full factorial of central composite design. An optimum working condition was suggested at pH sample (6.4), flow rate (1.2 ml/min) and elution volume of caffeine from sorbent is 9.5 ml of methanol. Detection and quantification limits were obtained at 0.02 and 0.25 ng/ml respectively. Good recovery was calculated within the range of 80.9 - 93.7 {\%} at three levels of concentration. Repeatability and reproducibility value show this method to be reliable for routine analysis with low RSD <10 {\%}. Concentration levels of caffeine in real samples were recorded in the range of 0.64 - 59.01 ng/ml. Hierarchical cluster analysis grouped all stations into three clusters at Dlink/Dmax x 100 <15. Wastewater discharge from cafeteria or residential area was a solid reason linked to the presence of high caffeine during this study.",
keywords = "Experimental design, Freshwater, Physcoactive drug, Response surface, Stimulant",
author = "Khalik, {Wan Mohd Afiq Wan Mohd} and Abdullah, {Md. Pauzi} and Baharudin, {Fatinah Khafizah} and Zulkepli, {Siti Aminah}",
year = "2016",
language = "English",
volume = "7",
pages = "720--728",
journal = "Journal of Materials and Environmental Science",
issn = "2028-2508",
publisher = "University of Mohammed Premier Oujda",
number = "3",

}

TY - JOUR

T1 - Optimization of extraction procedure for determination of caffeine residue in water

AU - Khalik, Wan Mohd Afiq Wan Mohd

AU - Abdullah, Md. Pauzi

AU - Baharudin, Fatinah Khafizah

AU - Zulkepli, Siti Aminah

PY - 2016

Y1 - 2016

N2 - Extraction procedure for determination of caffeine in water with aided experimental design was successfully optimized. Three variables, namely pH sample, flow rate and elution volume were tested during this study using 23 full factorial of central composite design. An optimum working condition was suggested at pH sample (6.4), flow rate (1.2 ml/min) and elution volume of caffeine from sorbent is 9.5 ml of methanol. Detection and quantification limits were obtained at 0.02 and 0.25 ng/ml respectively. Good recovery was calculated within the range of 80.9 - 93.7 % at three levels of concentration. Repeatability and reproducibility value show this method to be reliable for routine analysis with low RSD <10 %. Concentration levels of caffeine in real samples were recorded in the range of 0.64 - 59.01 ng/ml. Hierarchical cluster analysis grouped all stations into three clusters at Dlink/Dmax x 100 <15. Wastewater discharge from cafeteria or residential area was a solid reason linked to the presence of high caffeine during this study.

AB - Extraction procedure for determination of caffeine in water with aided experimental design was successfully optimized. Three variables, namely pH sample, flow rate and elution volume were tested during this study using 23 full factorial of central composite design. An optimum working condition was suggested at pH sample (6.4), flow rate (1.2 ml/min) and elution volume of caffeine from sorbent is 9.5 ml of methanol. Detection and quantification limits were obtained at 0.02 and 0.25 ng/ml respectively. Good recovery was calculated within the range of 80.9 - 93.7 % at three levels of concentration. Repeatability and reproducibility value show this method to be reliable for routine analysis with low RSD <10 %. Concentration levels of caffeine in real samples were recorded in the range of 0.64 - 59.01 ng/ml. Hierarchical cluster analysis grouped all stations into three clusters at Dlink/Dmax x 100 <15. Wastewater discharge from cafeteria or residential area was a solid reason linked to the presence of high caffeine during this study.

KW - Experimental design

KW - Freshwater

KW - Physcoactive drug

KW - Response surface

KW - Stimulant

UR - http://www.scopus.com/inward/record.url?scp=84959526928&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84959526928&partnerID=8YFLogxK

M3 - Article

VL - 7

SP - 720

EP - 728

JO - Journal of Materials and Environmental Science

JF - Journal of Materials and Environmental Science

SN - 2028-2508

IS - 3

ER -