Optimization hydrogenation process of D-glucose to D-sorbitol over Raney nickel catalyst

Muthanna J. Ahmed, Anees Abdullah Khadom, Abdul Amir H. Kadhum

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Hydrogenation of D-glucose in the presence of Raney nickel as a catalyst was employed for the preparation of D-sorbitol. The effects of the reaction time (15-90 min), reaction temperature (10-60°C), and catalyst to D-glucose ratio (5-15 wt %) on the yield of D-sorbitol were studied. The experimental design of Box-Wilson method was adopted to find a useful relationship between the effecting variables and the D-sorbitol yield. The experimental data collected by this design was successively fitted to a second order polynomial mathematical model. The analysis of variance shows that the catalyst to D-glucose ratio had the greatest effect on the yield of D-sorbitol among other variables. An optimum operating conditions of 67 min reaction time, 46 °C reaction temperature, and 14.5% catalyst to D-glucose ratio gave 87.15% D-sorbitol yield, 6.51% D-mannitol yield, and 95.93% D-glucose conversion. D-sorbitol of purity 99.8% was obtained after its separation from D-mannitol, the byproduct of the hydrogenation process, using the fractional crystallization method.

Original languageEnglish
Pages (from-to)294-304
Number of pages11
JournalEuropean Journal of Scientific Research
Volume30
Issue number2
Publication statusPublished - 2009

Fingerprint

Hydrogenation
hydrogenation
Sorbitol
Nickel
sorbitol
Process Optimization
Catalyst
Glucose
nickel
catalysts
glucose
catalyst
Catalysts
Reaction Time
Mannitol
mannitol
Polynomial Model
Analysis of variance
Crystallization
Analysis of variance (ANOVA)

Keywords

  • Box-Wilson design
  • Catalytic hydrogenation
  • D-glucose
  • D-sorbitol
  • Raney-Nickel

ASJC Scopus subject areas

  • General

Cite this

Optimization hydrogenation process of D-glucose to D-sorbitol over Raney nickel catalyst. / Ahmed, Muthanna J.; Khadom, Anees Abdullah; Kadhum, Abdul Amir H.

In: European Journal of Scientific Research, Vol. 30, No. 2, 2009, p. 294-304.

Research output: Contribution to journalArticle

Ahmed, Muthanna J. ; Khadom, Anees Abdullah ; Kadhum, Abdul Amir H. / Optimization hydrogenation process of D-glucose to D-sorbitol over Raney nickel catalyst. In: European Journal of Scientific Research. 2009 ; Vol. 30, No. 2. pp. 294-304.
@article{219b53c77a674733a6809c137e0e8cc3,
title = "Optimization hydrogenation process of D-glucose to D-sorbitol over Raney nickel catalyst",
abstract = "Hydrogenation of D-glucose in the presence of Raney nickel as a catalyst was employed for the preparation of D-sorbitol. The effects of the reaction time (15-90 min), reaction temperature (10-60°C), and catalyst to D-glucose ratio (5-15 wt {\%}) on the yield of D-sorbitol were studied. The experimental design of Box-Wilson method was adopted to find a useful relationship between the effecting variables and the D-sorbitol yield. The experimental data collected by this design was successively fitted to a second order polynomial mathematical model. The analysis of variance shows that the catalyst to D-glucose ratio had the greatest effect on the yield of D-sorbitol among other variables. An optimum operating conditions of 67 min reaction time, 46 °C reaction temperature, and 14.5{\%} catalyst to D-glucose ratio gave 87.15{\%} D-sorbitol yield, 6.51{\%} D-mannitol yield, and 95.93{\%} D-glucose conversion. D-sorbitol of purity 99.8{\%} was obtained after its separation from D-mannitol, the byproduct of the hydrogenation process, using the fractional crystallization method.",
keywords = "Box-Wilson design, Catalytic hydrogenation, D-glucose, D-sorbitol, Raney-Nickel",
author = "Ahmed, {Muthanna J.} and Khadom, {Anees Abdullah} and Kadhum, {Abdul Amir H.}",
year = "2009",
language = "English",
volume = "30",
pages = "294--304",
journal = "European Journal of Scientific Research",
issn = "1450-202X",
publisher = "European Journals Inc.",
number = "2",

}

TY - JOUR

T1 - Optimization hydrogenation process of D-glucose to D-sorbitol over Raney nickel catalyst

AU - Ahmed, Muthanna J.

AU - Khadom, Anees Abdullah

AU - Kadhum, Abdul Amir H.

PY - 2009

Y1 - 2009

N2 - Hydrogenation of D-glucose in the presence of Raney nickel as a catalyst was employed for the preparation of D-sorbitol. The effects of the reaction time (15-90 min), reaction temperature (10-60°C), and catalyst to D-glucose ratio (5-15 wt %) on the yield of D-sorbitol were studied. The experimental design of Box-Wilson method was adopted to find a useful relationship between the effecting variables and the D-sorbitol yield. The experimental data collected by this design was successively fitted to a second order polynomial mathematical model. The analysis of variance shows that the catalyst to D-glucose ratio had the greatest effect on the yield of D-sorbitol among other variables. An optimum operating conditions of 67 min reaction time, 46 °C reaction temperature, and 14.5% catalyst to D-glucose ratio gave 87.15% D-sorbitol yield, 6.51% D-mannitol yield, and 95.93% D-glucose conversion. D-sorbitol of purity 99.8% was obtained after its separation from D-mannitol, the byproduct of the hydrogenation process, using the fractional crystallization method.

AB - Hydrogenation of D-glucose in the presence of Raney nickel as a catalyst was employed for the preparation of D-sorbitol. The effects of the reaction time (15-90 min), reaction temperature (10-60°C), and catalyst to D-glucose ratio (5-15 wt %) on the yield of D-sorbitol were studied. The experimental design of Box-Wilson method was adopted to find a useful relationship between the effecting variables and the D-sorbitol yield. The experimental data collected by this design was successively fitted to a second order polynomial mathematical model. The analysis of variance shows that the catalyst to D-glucose ratio had the greatest effect on the yield of D-sorbitol among other variables. An optimum operating conditions of 67 min reaction time, 46 °C reaction temperature, and 14.5% catalyst to D-glucose ratio gave 87.15% D-sorbitol yield, 6.51% D-mannitol yield, and 95.93% D-glucose conversion. D-sorbitol of purity 99.8% was obtained after its separation from D-mannitol, the byproduct of the hydrogenation process, using the fractional crystallization method.

KW - Box-Wilson design

KW - Catalytic hydrogenation

KW - D-glucose

KW - D-sorbitol

KW - Raney-Nickel

UR - http://www.scopus.com/inward/record.url?scp=67649111462&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67649111462&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:67649111462

VL - 30

SP - 294

EP - 304

JO - European Journal of Scientific Research

JF - European Journal of Scientific Research

SN - 1450-202X

IS - 2

ER -