Optimization and validation of solid-phase microextraction of mercury species: An application of experimental design

Wan Mohd Afiq Wan Mohd Khalik, Md. Pauzi Abdullah, Fouad Fadhil Al-Qaim, Mohamed Rozali Othman, Yang Farina Abdul Aziz

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

In this study, determination of mercury species in water by headspace solid-phase microextraction (HS-SPME) has been developed. The extraction procedure consisted of screened using factorial design and followed by optimization using two level central composite designs. An optimum working condition was obtained at 22.5 °C after 20 min, pH 4 and stirring rate (200 rpm) with fixed values of salt addition (8.5 mg L-1) and sample volume (25 mL). Extraction was performed by using 100 μm polydimethylsiloxane (PDMS) fiber and desorption time at 1.2 min. Analytical figure of merit showed good linearity with R2 in the range of 0.992-0.994. Limit of detection and limit of quantification obtained were from 0.037 to 0.078 μg L-1 and from 0.124-0.178 μg L-1 for all analytes, respectively. Repeatability and reproducibility were good with relative standard deviation (RSD) <10 %. Recoveries were obtained in the range of 72-109 % at two levels of concentration.

Original languageEnglish
Pages (from-to)3803-3808
Number of pages6
JournalAsian Journal of Chemistry
Volume27
Issue number10
DOIs
Publication statusPublished - 1 Oct 2015

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Mercury
Design of experiments
Desorption
Salts
Recovery
Water
Fibers
Composite materials
baysilon

Keywords

  • Central composite design
  • Factorial design
  • Mercury
  • Response surface

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Optimization and validation of solid-phase microextraction of mercury species : An application of experimental design. / Khalik, Wan Mohd Afiq Wan Mohd; Abdullah, Md. Pauzi; Al-Qaim, Fouad Fadhil; Othman, Mohamed Rozali; Abdul Aziz, Yang Farina.

In: Asian Journal of Chemistry, Vol. 27, No. 10, 01.10.2015, p. 3803-3808.

Research output: Contribution to journalArticle

Khalik, Wan Mohd Afiq Wan Mohd ; Abdullah, Md. Pauzi ; Al-Qaim, Fouad Fadhil ; Othman, Mohamed Rozali ; Abdul Aziz, Yang Farina. / Optimization and validation of solid-phase microextraction of mercury species : An application of experimental design. In: Asian Journal of Chemistry. 2015 ; Vol. 27, No. 10. pp. 3803-3808.
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