Optic neuropathy in thyroid eye disease

A case series

Nur Aqilah Salleh, Wong Hon Seng, Hazlita Mohd Isa

Research output: Contribution to journalArticle

Abstract

In patients with thyroid disease, ocular involvement or thyroid ophthalmopathy is common, irrespective of their thyroid status. A common feature of thyroid eye disease is eyelid retraction, which leads to a classical starry gaze (Kocher sign). Treatment with radioactive iodine (RAI) is a known therapy for hyperthyroidism. However, this treat-ment may lead to or worsen thyroid ophthalmopathy. We report a case series of two patients with thyrotoxicosis, who presented with an atypical and subtle occurrence of thyroid eye disease (TED) soon after RAI therapy. One of the patients was initially diagnosed and treated for dry eyes; however, over a period of time, the patient's vision pro-gressively deteriorated. Clinical and radiological investigations confirmed thyroid ophthalmopathy with low serum thyroid hormone levels. Both patients recovered well after immediate intensive intravenous steroid treatment. These cases highlight the importance of recognizing partial ptosis as one of the presenting signs of active TED among general practitioners and physicians.

Original languageEnglish
Pages (from-to)197-201
Number of pages5
JournalKorean Journal of Family Medicine
Volume37
Issue number3
DOIs
Publication statusPublished - 2016

Fingerprint

Optic Nerve Diseases
Eye Diseases
Thyroid Diseases
Thyroid Gland
Iodine
Thyrotoxicosis
Eyelids
Hyperthyroidism
Therapeutics
Thyroid Hormones
General Practitioners
Steroids
Physicians
Serum

Keywords

  • Proptosis
  • Ptosis
  • Radioactive iodine
  • Relative afferent pupillary defect
  • Thyroid eye disease

ASJC Scopus subject areas

  • Family Practice

Cite this

Optic neuropathy in thyroid eye disease : A case series. / Salleh, Nur Aqilah; Seng, Wong Hon; Mohd Isa, Hazlita.

In: Korean Journal of Family Medicine, Vol. 37, No. 3, 2016, p. 197-201.

Research output: Contribution to journalArticle

Salleh, Nur Aqilah ; Seng, Wong Hon ; Mohd Isa, Hazlita. / Optic neuropathy in thyroid eye disease : A case series. In: Korean Journal of Family Medicine. 2016 ; Vol. 37, No. 3. pp. 197-201.
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