Oligostilbenoids from Vatica pauciflora and the oxidative effect on chang cells

Aisyah Salihah Kamarozaman, Jalifah Latip, Yana M. Syah, Nor Fadilah Rajab, Anuar Jaloh

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Phytochemical studies on the woods and twigs of Vatica pauciflora (Dipterocarpaceae) have been conducted. The woods and twigs of V. pauciflora were extracted in methanol and ethanol respectively with Soxhlet apparatus. The crude methanol extracts from the woods were semi-purified by vacuum liquid chromatography to give 14 fractions (VMB01-VMB14). The VMB10 was further purified by radial chromatography to give pure dimmer stilbenoid. The same technique has been employed on the crude ethanol extracts from the twigs in which one pure fraction, VER612 was obtained. Based on the UV, IR, NMR and mass spectral data, the pure compounds were characterized as ε-viniferin and vaticanol G respectively. An oxidative damage test which was done on Chang liver cells has shown that ε-viniferin has a potential to be a chemopreventive agent to protect liver cells from oxidative damage.

Original languageEnglish
Article number012045
JournalJournal of Physics: Conference Series
Volume423
Issue number1
DOIs
Publication statusPublished - 2013

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liver
ethyl alcohol
methyl alcohol
cells
damage
liquid chromatography
chromatography
vacuum
nuclear magnetic resonance

Keywords

  • ε-viniferin
  • Vatica pauciflora
  • Vaticanol G and chemopreventive

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Oligostilbenoids from Vatica pauciflora and the oxidative effect on chang cells. / Kamarozaman, Aisyah Salihah; Latip, Jalifah; Syah, Yana M.; Rajab, Nor Fadilah; Jaloh, Anuar.

In: Journal of Physics: Conference Series, Vol. 423, No. 1, 012045, 2013.

Research output: Contribution to journalArticle

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