Olea europaea and its constituents promote bone health by enhancing osteoblast differentiation and proliferation

A review

Ruszymah Idrus, Aminuddin Bin Saim

Research output: Contribution to journalReview article

Abstract

Background: The human bone is in a constant state of balance between bone resorption and bone formation, maintained by the osteoclasts and osteoblasts respectively. Association of Mediterranean diet and bone health has been prevalently studied in recent years. Olive and its constituents have been suggested to be the major contributor to the benefits of the Mediterranean diet in bone health. Method: In this review, cellular and molecular mechanism of bone homeostasis and the influence of olive and its constituents were discussed. Result: Many studies ranging from clinical, animal and in vitro cell culture reported benefits of olive and its constituents in bone health. Olive and its constituent exerted its beneficial effect in bone health through stimulation of bone formation as opposed to inhibition of bone resorption. Conclusion: Olive and its constituents promotes osteoblast differentiation and proliferation.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalPharmacognosy Journal
Volume11
Issue number1
DOIs
Publication statusPublished - 1 Jan 2019

Fingerprint

Olea
Osteoblasts
Bone and Bones
Health
Mediterranean Diet
Bone Resorption
Osteogenesis
Osteoclasts
Homeostasis
Cell Culture Techniques

Keywords

  • Bone
  • Hydroxytyrosol
  • Oleuropein
  • Olive
  • Osteoblast

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

Cite this

Olea europaea and its constituents promote bone health by enhancing osteoblast differentiation and proliferation : A review. / Idrus, Ruszymah; Saim, Aminuddin Bin.

In: Pharmacognosy Journal, Vol. 11, No. 1, 01.01.2019, p. 1-7.

Research output: Contribution to journalReview article

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