Off-pump coronary artery bypass graft surgery in patients with left main stem disease

I. M. Ishamuddin, D. M. Zamrin, Ooi Joanna Su Min, Mohd Ramzisham Abdul Rahman, H. Hairolfaizi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: The safety, feasibility and post-operative outcome are the main concern in Off-pump Coronary artery bypass graft (OPCAB) surgery as compared to conventional technique especially in multivessels coronary artery disease. Materials and Methods: A cross-sectional study was conducted on 137 patients with left main stem disease (LMS) who underwent Coronary artery bypass graft surgery (CABG) between January 2001 and August 2009 to compare the outcome between off-pump and on-pump CABG. Results: The mean age was 59.7 ±1.3 years. Off-pump CABG was conducted in 52 (37.95%) and on-pump CABG in 85 (62.05%) cases. There were no signifi cant difference in age, race and BMI between the groups. Off-pump groups had signifi cantly higher EuroSCORE, reduced LVEF, milder left main stem stenosis, lower NYHA score, higher post-operative intra-operative balloon pump insertion (IABP). No signifi cant difference in the number of graft used, LIMA usage and amount of blood loss within the fi rst 24 hours post operatively. More patients in on-pump group had post-operative bleeding (23.5% vs 9.6%, p=0.046) and required more blood product transfusions (p<0.01). There were 3 (5.8%) deaths in off-pump group, 6 (7.1%) in on-pump and 1 (0.7%) in on-pump beating heart groups (p=0.780). Conclusion. The results of this study showed that Off-pump CABG is equally safe and effective technique for left main stem disease as compared to the conventional on-pump CABG.

Original languageEnglish
Pages (from-to)527-531
Number of pages5
JournalClinica Terapeutica
Volume162
Issue number6
Publication statusPublished - 2011

Fingerprint

Off-Pump Coronary Artery Bypass
Coronary Artery Bypass
Transplants
Blood Transfusion
Coronary Artery Disease
Pathologic Constriction
Cross-Sectional Studies
Hemorrhage
Safety

Keywords

  • Cardiothoracic
  • Coronary artery disease
  • LMS disease
  • Off-pump CABG
  • Surgery

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Off-pump coronary artery bypass graft surgery in patients with left main stem disease. / Ishamuddin, I. M.; Zamrin, D. M.; Su Min, Ooi Joanna; Abdul Rahman, Mohd Ramzisham; Hairolfaizi, H.

In: Clinica Terapeutica, Vol. 162, No. 6, 2011, p. 527-531.

Research output: Contribution to journalArticle

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abstract = "Background: The safety, feasibility and post-operative outcome are the main concern in Off-pump Coronary artery bypass graft (OPCAB) surgery as compared to conventional technique especially in multivessels coronary artery disease. Materials and Methods: A cross-sectional study was conducted on 137 patients with left main stem disease (LMS) who underwent Coronary artery bypass graft surgery (CABG) between January 2001 and August 2009 to compare the outcome between off-pump and on-pump CABG. Results: The mean age was 59.7 ±1.3 years. Off-pump CABG was conducted in 52 (37.95{\%}) and on-pump CABG in 85 (62.05{\%}) cases. There were no signifi cant difference in age, race and BMI between the groups. Off-pump groups had signifi cantly higher EuroSCORE, reduced LVEF, milder left main stem stenosis, lower NYHA score, higher post-operative intra-operative balloon pump insertion (IABP). No signifi cant difference in the number of graft used, LIMA usage and amount of blood loss within the fi rst 24 hours post operatively. More patients in on-pump group had post-operative bleeding (23.5{\%} vs 9.6{\%}, p=0.046) and required more blood product transfusions (p<0.01). There were 3 (5.8{\%}) deaths in off-pump group, 6 (7.1{\%}) in on-pump and 1 (0.7{\%}) in on-pump beating heart groups (p=0.780). Conclusion. The results of this study showed that Off-pump CABG is equally safe and effective technique for left main stem disease as compared to the conventional on-pump CABG.",
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