Occurrence of synthetic hormones in sewage effluents and Langat River and its tributaries, Malaysia

Najat Ahmed Al-Odaini, Mohamad Pauzi Zakaria, Mohamad Ismail Yaziz, Salmijah Surif, Narayanan Kannan

    Research output: Contribution to journalArticle

    11 Citations (Scopus)

    Abstract

    This study investigated for the first time the occurrence of selected synthetic hormones including 17α-ethinylestradiol, levonorgestrel, norethindrone and cyproterone acetate in Malaysian tropical waters. Samples were collected from the effluents of five sewage treatment plants (STPs) and at seven stations along the Langat River in Selangor, Malaysia, and its main tributaries. Samples were extracted by solid phase extraction (SPE) and analyzed by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). In Langat river samples, only levonorgestrel and cyproterone acetate were found at 50% and 3.3% frequency. The concentrations detected for levonorgestrel ranged from less than the method detection limit (<MDL) to 213 ng L-1 and from < MDL to 76 ng L-1 for cyproterone acetate. For the STP effluent samples, levonorgestrel was <MDL in all samples and the concentrations detected were in the range < MDL - 262 ng L-1 for cyproterone acetate, < MDL -11336 ng L-1 for norethindrone and < MDL - 1898 ng L-1 for 17α-ethinylestradiol.

    Original languageEnglish
    Pages (from-to)1457-1469
    Number of pages13
    JournalInternational Journal of Environmental Analytical Chemistry
    Volume93
    Issue number14
    DOIs
    Publication statusPublished - 2013

    Fingerprint

    Cyproterone Acetate
    synthetic hormones
    Sewage treatment plants
    Levonorgestrel
    sewage effluent
    Malaysia
    Hormones
    Sewage
    Rivers
    hormone
    Effluents
    tributary
    acetate
    sewage
    effluent
    Ethinyl Estradiol
    rivers
    acetates
    Liquid chromatography
    sewage treatment

    Keywords

    • aquatic pollution
    • Malaysian Rivers
    • sewage effluents
    • synthetic hormones

    ASJC Scopus subject areas

    • Water Science and Technology
    • Waste Management and Disposal
    • Pollution
    • Public Health, Environmental and Occupational Health
    • Health, Toxicology and Mutagenesis
    • Environmental Chemistry
    • Analytical Chemistry
    • Soil Science

    Cite this

    Occurrence of synthetic hormones in sewage effluents and Langat River and its tributaries, Malaysia. / Al-Odaini, Najat Ahmed; Zakaria, Mohamad Pauzi; Yaziz, Mohamad Ismail; Surif, Salmijah; Kannan, Narayanan.

    In: International Journal of Environmental Analytical Chemistry, Vol. 93, No. 14, 2013, p. 1457-1469.

    Research output: Contribution to journalArticle

    Al-Odaini, Najat Ahmed ; Zakaria, Mohamad Pauzi ; Yaziz, Mohamad Ismail ; Surif, Salmijah ; Kannan, Narayanan. / Occurrence of synthetic hormones in sewage effluents and Langat River and its tributaries, Malaysia. In: International Journal of Environmental Analytical Chemistry. 2013 ; Vol. 93, No. 14. pp. 1457-1469.
    @article{c43e1dc4d1ea41d0afbf162bf19f3764,
    title = "Occurrence of synthetic hormones in sewage effluents and Langat River and its tributaries, Malaysia",
    abstract = "This study investigated for the first time the occurrence of selected synthetic hormones including 17α-ethinylestradiol, levonorgestrel, norethindrone and cyproterone acetate in Malaysian tropical waters. Samples were collected from the effluents of five sewage treatment plants (STPs) and at seven stations along the Langat River in Selangor, Malaysia, and its main tributaries. Samples were extracted by solid phase extraction (SPE) and analyzed by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). In Langat river samples, only levonorgestrel and cyproterone acetate were found at 50{\%} and 3.3{\%} frequency. The concentrations detected for levonorgestrel ranged from less than the method detection limit (<MDL) to 213 ng L-1 and from < MDL to 76 ng L-1 for cyproterone acetate. For the STP effluent samples, levonorgestrel was <MDL in all samples and the concentrations detected were in the range < MDL - 262 ng L-1 for cyproterone acetate, < MDL -11336 ng L-1 for norethindrone and < MDL - 1898 ng L-1 for 17α-ethinylestradiol.",
    keywords = "aquatic pollution, Malaysian Rivers, sewage effluents, synthetic hormones",
    author = "Al-Odaini, {Najat Ahmed} and Zakaria, {Mohamad Pauzi} and Yaziz, {Mohamad Ismail} and Salmijah Surif and Narayanan Kannan",
    year = "2013",
    doi = "10.1080/03067319.2012.727810",
    language = "English",
    volume = "93",
    pages = "1457--1469",
    journal = "International Journal of Environmental Analytical Chemistry",
    issn = "0306-7319",
    publisher = "Taylor and Francis Ltd.",
    number = "14",

    }

    TY - JOUR

    T1 - Occurrence of synthetic hormones in sewage effluents and Langat River and its tributaries, Malaysia

    AU - Al-Odaini, Najat Ahmed

    AU - Zakaria, Mohamad Pauzi

    AU - Yaziz, Mohamad Ismail

    AU - Surif, Salmijah

    AU - Kannan, Narayanan

    PY - 2013

    Y1 - 2013

    N2 - This study investigated for the first time the occurrence of selected synthetic hormones including 17α-ethinylestradiol, levonorgestrel, norethindrone and cyproterone acetate in Malaysian tropical waters. Samples were collected from the effluents of five sewage treatment plants (STPs) and at seven stations along the Langat River in Selangor, Malaysia, and its main tributaries. Samples were extracted by solid phase extraction (SPE) and analyzed by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). In Langat river samples, only levonorgestrel and cyproterone acetate were found at 50% and 3.3% frequency. The concentrations detected for levonorgestrel ranged from less than the method detection limit (<MDL) to 213 ng L-1 and from < MDL to 76 ng L-1 for cyproterone acetate. For the STP effluent samples, levonorgestrel was <MDL in all samples and the concentrations detected were in the range < MDL - 262 ng L-1 for cyproterone acetate, < MDL -11336 ng L-1 for norethindrone and < MDL - 1898 ng L-1 for 17α-ethinylestradiol.

    AB - This study investigated for the first time the occurrence of selected synthetic hormones including 17α-ethinylestradiol, levonorgestrel, norethindrone and cyproterone acetate in Malaysian tropical waters. Samples were collected from the effluents of five sewage treatment plants (STPs) and at seven stations along the Langat River in Selangor, Malaysia, and its main tributaries. Samples were extracted by solid phase extraction (SPE) and analyzed by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). In Langat river samples, only levonorgestrel and cyproterone acetate were found at 50% and 3.3% frequency. The concentrations detected for levonorgestrel ranged from less than the method detection limit (<MDL) to 213 ng L-1 and from < MDL to 76 ng L-1 for cyproterone acetate. For the STP effluent samples, levonorgestrel was <MDL in all samples and the concentrations detected were in the range < MDL - 262 ng L-1 for cyproterone acetate, < MDL -11336 ng L-1 for norethindrone and < MDL - 1898 ng L-1 for 17α-ethinylestradiol.

    KW - aquatic pollution

    KW - Malaysian Rivers

    KW - sewage effluents

    KW - synthetic hormones

    UR - http://www.scopus.com/inward/record.url?scp=84890637967&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=84890637967&partnerID=8YFLogxK

    U2 - 10.1080/03067319.2012.727810

    DO - 10.1080/03067319.2012.727810

    M3 - Article

    AN - SCOPUS:84890637967

    VL - 93

    SP - 1457

    EP - 1469

    JO - International Journal of Environmental Analytical Chemistry

    JF - International Journal of Environmental Analytical Chemistry

    SN - 0306-7319

    IS - 14

    ER -