Novel macromolecules derived from coumarin

Synthesis and antioxidant activity

Ahmed A. Al-Amiery, Yasameen K. Al-Majedy, Abdul Amir H. Kadhum, Abu Bakar Mohamad

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The rational design of 4-hydroxycoumarins with tailor-made antioxidant activities is required nowadays due to the wide variety of pharmacologically significant, structurally interesting of coumarins and researcher orientation toward green chemistry and natural products. A simple and unique coumarins have been achieved by reaction of 4-hydroxycoumarin with aromatic aldehyde accompanied with the creation of a macromolecules have 2-aminothiazolidin-4-one. The molecular structures of the compounds were characterized by the Fourier transformation infrared and Nuclear magnetic resonance spectroscopies, in addition to CHN analysis. The scavenging abilities of new compounds against stable DPPH radical (DPPH) and hydrogen peroxide were done and the results show that the compounds exhibited high antioxidant activates.

Original languageEnglish
Article number11825
JournalScientific Reports
Volume5
DOIs
Publication statusPublished - 2 Jul 2015

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Coumarins
4-Hydroxycoumarins
Antioxidants
Molecular Structure
Biological Products
Aldehydes
Hydrogen Peroxide
Magnetic Resonance Spectroscopy
Research Personnel
coumarin
4-hydroxycoumarin

ASJC Scopus subject areas

  • General

Cite this

Novel macromolecules derived from coumarin : Synthesis and antioxidant activity. / Al-Amiery, Ahmed A.; Al-Majedy, Yasameen K.; Kadhum, Abdul Amir H.; Mohamad, Abu Bakar.

In: Scientific Reports, Vol. 5, 11825, 02.07.2015.

Research output: Contribution to journalArticle

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