Non-invasive Techniques for Assessing the Endothelial Dysfunction: Ultrasound Versus Photoplethysmography

M. Zaheditochai, Rosmina Jaafar, E. Zahedi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

Endothelial dysfunction, which can be noninvasively assessed by flow mediated vasodilation (FMD), predicts an increased rate of adverse cardiovascular events. The endothelial dysfunction is considered as a leading cause of development and progression of the atherosclerotic process. The main aim of this study is to review different non-invasive methods to assess the endothelial dysfunction and to propose enhancements to a new method based on photoplethysmography (PPG). First, non-invasive techniques developed for the evaluation of peripheral endothelial function (including the Doppler ultrasound (US)) will be reviewed. Although noninvasive, US -based techniques present a few disadvantages. To remedy to the above disadvantages, another technique based on pulse wave analysis is introduced. Although amplitudebased features from the photoplethysmogram has produced encouraging results, there are cases where the complete equivalence with US-FMD based on ultrasound measurement cannot be established. Therefore more elaborated features combined with data processing techniques are proposed which seem promising enough for the PPG-based technique to be used as a replacement method for US-FMD measurement. The ultimate aim is to assess the endothelial function and the presence of significant atherosclerotic events leading to peripheral vascular disease using a practical, simple, low-cost, nonoperator dependent and alternative non-invasive technique in a clinical setting.

Original languageEnglish
Title of host publicationIFMBE Proceedings
Pages65-68
Number of pages4
Volume23
DOIs
Publication statusPublished - 2009
Event13th International Conference on Biomedical Engineering, ICBME 2008 -
Duration: 3 Dec 20086 Dec 2008

Other

Other13th International Conference on Biomedical Engineering, ICBME 2008
Period3/12/086/12/08

Fingerprint

Photoplethysmography
Ultrasonics
Vasodilation
Costs

Keywords

  • Endothelial function
  • Flow mediated vasodilation
  • Photoplethysmography

ASJC Scopus subject areas

  • Biomedical Engineering
  • Bioengineering

Cite this

Non-invasive Techniques for Assessing the Endothelial Dysfunction : Ultrasound Versus Photoplethysmography. / Zaheditochai, M.; Jaafar, Rosmina; Zahedi, E.

IFMBE Proceedings. Vol. 23 2009. p. 65-68.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zaheditochai, M, Jaafar, R & Zahedi, E 2009, Non-invasive Techniques for Assessing the Endothelial Dysfunction: Ultrasound Versus Photoplethysmography. in IFMBE Proceedings. vol. 23, pp. 65-68, 13th International Conference on Biomedical Engineering, ICBME 2008, 3/12/08. https://doi.org/10.1007/978-3-540-92841-6_16
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