NOMID: The radiographic and MRI features and review of literature

Faizah Mohd Zaki, Radhika Sridharan, Tan Sook Pei, Sharaf Ibrahim, Tang Swee Ping

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Neonatal onset multisystem inflammatory disease (NOMID) is a rare autoinflammatory disorder, which manifests early in infancy. We describe a case of a 10-year-old boy who has been unwell since infancy. He presented with urticarial rash, intermittent fever and hepatosplenomegaly followed by progressive arthropathy. His joint symptoms started at two years of age, which progressively involved multiple joints, resulting in bone and joint deformities. A series of joint radiographs demonstrated bizarre enlarging physeal mass with heterogenous calcification. Magnetic resonance imaging (MRI) of the involved right ankle and knee showed characteristic thickened and calcified physeal lesions, which enhanced post-gadolinium. This debilitating disease is also known to involve the central nervous system and eyes. This case report aims to highlight the conventional radiographic and magnetic resonance imaging (MRI) findings of this physeal abnormality in NOMID syndrome.

Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalJournal of Radiology Case Reports
Volume6
Issue number3
DOIs
Publication statusPublished - 2012

Fingerprint

Cryopyrin-Associated Periodic Syndromes
Joints
Magnetic Resonance Imaging
Joint Diseases
Gadolinium
Exanthema
Ankle
Knee
Fever
Central Nervous System
Bone and Bones

Keywords

  • Cinca
  • Mri
  • Neonate
  • Nomid
  • Radiograph

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

NOMID : The radiographic and MRI features and review of literature. / Mohd Zaki, Faizah; Sridharan, Radhika; Pei, Tan Sook; Ibrahim, Sharaf; Ping, Tang Swee.

In: Journal of Radiology Case Reports, Vol. 6, No. 3, 2012, p. 1-8.

Research output: Contribution to journalArticle

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