Nocardiosis causing hypocellular bone marrow after allogeneic peripheral blood stem cell transplantation

Research output: Contribution to journalArticle

Abstract

Nocardia infection is rare in bone marrow transplant (BMT) recipients with less than 30 cases reported in the literature [1-4]. The majority of the cases occurred late in the post-transplant period. Common clinical presentations included formation of widespread and multiple abscesses. Bone marrow hypoplasia is an uncommon finding. We describe the first case of nocardiosis, diagnosed at day 100 after non-myeloablative allogeneic peripheral blood stem cell transplantation, presenting as pancytopenia and hypocellular marrow. Eradication of the infection with antibiotics resulted in complete hematological recovery.

Original languageEnglish
Pages (from-to)337-339
Number of pages3
JournalHematology
Volume6
Issue number5
Publication statusPublished - 2001

Fingerprint

Nocardia Infections
Peripheral Blood Stem Cell Transplantation
Bone Marrow
Pancytopenia
Abscess
Anti-Bacterial Agents
Transplants
Infection

Keywords

  • Bone marrow transplantation (BMT)
  • Hypocellular marrow
  • Nocardiosis
  • Non-myeloablative
  • Peripheral blood stem cell transplantation (PBSCT)

ASJC Scopus subject areas

  • Hematology

Cite this

@article{d79cbf0e07b44216916b648337be2c7d,
title = "Nocardiosis causing hypocellular bone marrow after allogeneic peripheral blood stem cell transplantation",
abstract = "Nocardia infection is rare in bone marrow transplant (BMT) recipients with less than 30 cases reported in the literature [1-4]. The majority of the cases occurred late in the post-transplant period. Common clinical presentations included formation of widespread and multiple abscesses. Bone marrow hypoplasia is an uncommon finding. We describe the first case of nocardiosis, diagnosed at day 100 after non-myeloablative allogeneic peripheral blood stem cell transplantation, presenting as pancytopenia and hypocellular marrow. Eradication of the infection with antibiotics resulted in complete hematological recovery.",
keywords = "Bone marrow transplantation (BMT), Hypocellular marrow, Nocardiosis, Non-myeloablative, Peripheral blood stem cell transplantation (PBSCT)",
author = "{S. Abdul Wahid}, {S Fadilah} and Cheong, {S. K.} and Ali, {Raymond Azman} and Norlela Sukor",
year = "2001",
language = "English",
volume = "6",
pages = "337--339",
journal = "Hematology",
issn = "1024-5332",
publisher = "Taylor and Francis Ltd.",
number = "5",

}

TY - JOUR

T1 - Nocardiosis causing hypocellular bone marrow after allogeneic peripheral blood stem cell transplantation

AU - S. Abdul Wahid, S Fadilah

AU - Cheong, S. K.

AU - Ali, Raymond Azman

AU - Sukor, Norlela

PY - 2001

Y1 - 2001

N2 - Nocardia infection is rare in bone marrow transplant (BMT) recipients with less than 30 cases reported in the literature [1-4]. The majority of the cases occurred late in the post-transplant period. Common clinical presentations included formation of widespread and multiple abscesses. Bone marrow hypoplasia is an uncommon finding. We describe the first case of nocardiosis, diagnosed at day 100 after non-myeloablative allogeneic peripheral blood stem cell transplantation, presenting as pancytopenia and hypocellular marrow. Eradication of the infection with antibiotics resulted in complete hematological recovery.

AB - Nocardia infection is rare in bone marrow transplant (BMT) recipients with less than 30 cases reported in the literature [1-4]. The majority of the cases occurred late in the post-transplant period. Common clinical presentations included formation of widespread and multiple abscesses. Bone marrow hypoplasia is an uncommon finding. We describe the first case of nocardiosis, diagnosed at day 100 after non-myeloablative allogeneic peripheral blood stem cell transplantation, presenting as pancytopenia and hypocellular marrow. Eradication of the infection with antibiotics resulted in complete hematological recovery.

KW - Bone marrow transplantation (BMT)

KW - Hypocellular marrow

KW - Nocardiosis

KW - Non-myeloablative

KW - Peripheral blood stem cell transplantation (PBSCT)

UR - http://www.scopus.com/inward/record.url?scp=0035663607&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035663607&partnerID=8YFLogxK

M3 - Article

VL - 6

SP - 337

EP - 339

JO - Hematology

JF - Hematology

SN - 1024-5332

IS - 5

ER -