N,N-Dimethylacetamide

Ahmad Rohi Ghazali, S. H. Inayat-Hussain

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Abstract

N,N-dimethylacetamide (DMAC; CAS: 127-19-5) is a potent industrial solvent and also an intermediate for many organic reactions in the synthesis of agrochemicals, pharmaceuticals, and fine chemicals. Occupational exposures can occur through inhalation of its vapor and dermal contact. It is readily absorbed in humans after oral, dermal, or inhalation exposure. DMAC human exposure mainly causes liver toxicity but is less toxic to the environment. Recently, DMAC has been listed as a chemical known to cause reproductive toxicity.

Original languageEnglish
Title of host publicationEncyclopedia of Toxicology
Subtitle of host publicationThird Edition
PublisherElsevier
Pages594-597
Number of pages4
ISBN (Electronic)9780123864543
ISBN (Print)9780123864550
DOIs
Publication statusPublished - 1 Jan 2014

Fingerprint

Agrochemicals
Inhalation Exposure
Skin
Poisons
Occupational Exposure
Inhalation
Liver
Pharmaceutical Preparations
dimethylacetamide

Keywords

  • Developmental toxicity
  • Hepatotoxicity
  • N,N-dimethylacetamide
  • N-monomethylacetamide
  • Solvent

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Ghazali, A. R., & Inayat-Hussain, S. H. (2014). N,N-Dimethylacetamide. In Encyclopedia of Toxicology: Third Edition (pp. 594-597). Elsevier. https://doi.org/10.1016/B978-0-12-386454-3.01223-9

N,N-Dimethylacetamide. / Ghazali, Ahmad Rohi; Inayat-Hussain, S. H.

Encyclopedia of Toxicology: Third Edition. Elsevier, 2014. p. 594-597.

Research output: Chapter in Book/Report/Conference proceedingChapter

Ghazali, AR & Inayat-Hussain, SH 2014, N,N-Dimethylacetamide. in Encyclopedia of Toxicology: Third Edition. Elsevier, pp. 594-597. https://doi.org/10.1016/B978-0-12-386454-3.01223-9
Ghazali AR, Inayat-Hussain SH. N,N-Dimethylacetamide. In Encyclopedia of Toxicology: Third Edition. Elsevier. 2014. p. 594-597 https://doi.org/10.1016/B978-0-12-386454-3.01223-9
Ghazali, Ahmad Rohi ; Inayat-Hussain, S. H. / N,N-Dimethylacetamide. Encyclopedia of Toxicology: Third Edition. Elsevier, 2014. pp. 594-597
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