Nitrite detection using plastic optical fiber (POF); An early stage investigation towards the development of oral cancer sensor using POF

Sayidatul Nadia Elias, Norhana Arsad, Sabiran Abubakar

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Oral Squamous Cell Carcinoma (OSCC) has a higher chance of survival rate if being detected at an early stage. Overconsumption of nitrite in human body may result in OSCC formation. Nitrite and nitrate is a part of reactive nitrogen species (RNS) in saliva and is found to have higher percentage in OSCC patients' saliva, thus chosen to be investigated as a potential OSCC biomarker using plastic optical fiber (POF) with evanescent wave sensing method. The experiment is done using UV/vis light source and the peak absorbance is found to be approximately 540 nm. The sensor displays moderate sensitivity with higher sensitivity towards lower end of the concentration.

Original languageEnglish
Pages (from-to)2908-2911
Number of pages4
JournalOptik
Volume126
Issue number21
DOIs
Publication statusPublished - 1 Nov 2015

Fingerprint

Plastic optical fibers
plastic fibers
nitrites
Nitrites
optical fibers
cancer
saliva
sensors
Sensors
Reactive Nitrogen Species
biomarkers
sensitivity
evanescent waves
human body
Biomarkers
Ultraviolet radiation
Nitrates
nitrates
light sources
Nitrogen

Keywords

  • Beer-Lambert law
  • Evanescent wave sensing
  • Nitrite
  • OSCC
  • Plastic optical fiber

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Electrical and Electronic Engineering
  • Atomic and Molecular Physics, and Optics

Cite this

Nitrite detection using plastic optical fiber (POF); An early stage investigation towards the development of oral cancer sensor using POF. / Elias, Sayidatul Nadia; Arsad, Norhana; Abubakar, Sabiran.

In: Optik, Vol. 126, No. 21, 01.11.2015, p. 2908-2911.

Research output: Contribution to journalArticle

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