New myrsinane-type diterpenoids from Euphorbia aellenii Rech. f. with their immunomodulatory activity

Abdul Majid Ayatollahi, Mustafa Ghanadian, Osman Mesaik Mohammed Ahmed Hassan, Omer Mohamed Abdella, Suleiman Afsharypuor, Farzad Kobarfard, Marjan Mirza-Taheri

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Two new 14-desoxo-10, 18-dihydromyrinsol diterpenoids (1 and 2) were isolated and characterized from the cytotoxic chloroform fraction of Euphorbia aellenii Rech. f. (Euphorbiaceae). The structures of the new compounds were elucidated by spectroscopic methods and their immunomodulatory properties were evaluated by T-cell proliferation and phagocyte chemiluminescence assays.

Original languageEnglish
Pages (from-to)1020-1025
Number of pages6
JournalJournal of Asian Natural Products Research
Volume12
Issue number12
DOIs
Publication statusPublished - Dec 2010
Externally publishedYes

Fingerprint

Euphorbiaceae
Euphorbia
Chemiluminescence
T-cells
Diterpenes
Cell proliferation
Phagocytes
Chloroform
Luminescence
Assays
Cell Proliferation
T-Lymphocytes

Keywords

  • 10,18-dihydromyrinsol diterpenes
  • Euphorbia aellenii
  • immunomodulatory effect
  • myrsinane

ASJC Scopus subject areas

  • Complementary and alternative medicine
  • Molecular Medicine
  • Organic Chemistry
  • Analytical Chemistry
  • Pharmaceutical Science
  • Pharmacology
  • Drug Discovery

Cite this

Ayatollahi, A. M., Ghanadian, M., Mohammed Ahmed Hassan, O. M., Mohamed Abdella, O., Afsharypuor, S., Kobarfard, F., & Mirza-Taheri, M. (2010). New myrsinane-type diterpenoids from Euphorbia aellenii Rech. f. with their immunomodulatory activity. Journal of Asian Natural Products Research, 12(12), 1020-1025. https://doi.org/10.1080/10286020.2010.529611

New myrsinane-type diterpenoids from Euphorbia aellenii Rech. f. with their immunomodulatory activity. / Ayatollahi, Abdul Majid; Ghanadian, Mustafa; Mohammed Ahmed Hassan, Osman Mesaik; Mohamed Abdella, Omer; Afsharypuor, Suleiman; Kobarfard, Farzad; Mirza-Taheri, Marjan.

In: Journal of Asian Natural Products Research, Vol. 12, No. 12, 12.2010, p. 1020-1025.

Research output: Contribution to journalArticle

Ayatollahi, AM, Ghanadian, M, Mohammed Ahmed Hassan, OM, Mohamed Abdella, O, Afsharypuor, S, Kobarfard, F & Mirza-Taheri, M 2010, 'New myrsinane-type diterpenoids from Euphorbia aellenii Rech. f. with their immunomodulatory activity', Journal of Asian Natural Products Research, vol. 12, no. 12, pp. 1020-1025. https://doi.org/10.1080/10286020.2010.529611
Ayatollahi AM, Ghanadian M, Mohammed Ahmed Hassan OM, Mohamed Abdella O, Afsharypuor S, Kobarfard F et al. New myrsinane-type diterpenoids from Euphorbia aellenii Rech. f. with their immunomodulatory activity. Journal of Asian Natural Products Research. 2010 Dec;12(12):1020-1025. https://doi.org/10.1080/10286020.2010.529611
Ayatollahi, Abdul Majid ; Ghanadian, Mustafa ; Mohammed Ahmed Hassan, Osman Mesaik ; Mohamed Abdella, Omer ; Afsharypuor, Suleiman ; Kobarfard, Farzad ; Mirza-Taheri, Marjan. / New myrsinane-type diterpenoids from Euphorbia aellenii Rech. f. with their immunomodulatory activity. In: Journal of Asian Natural Products Research. 2010 ; Vol. 12, No. 12. pp. 1020-1025.
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