Diterpenoid-diterpenoid terbaharu daripada akar Croton hirtus (Euphorbiaceae)

Translated title of the contribution: New diterpenoids from the roots of Croton hirtus (Euphorbiaceae)

Andi Rifki Rosandy, Anis Asmi Azman, Rozida Mohd. Khalid, Rizafizah Othaman, Mohamad Azwani Shah Mat Lazim, Iqbal M. Choudary, Yana Maulana Syah, Jalifah Latip, Ikram Md Said, Muntaz Abu Bakar

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The root of Croton hirtus was collected at Tanjung Sepat, Banting for study of its chemical compounds. This sample was dried before being ground and extracted using the methanol solvent at room temperature for three days yielding 18.25 gram of crude extract. The crude extracts obtained were analysed using thin layer chromatography (TLC) then fractionated via vacuum column chromatography (VLC) and proceed the isolation using radial chromatography (RC) to get the pure compounds. The pure compounds obtained were elucidated by nuclear magnetic resonance (NMR), Fourier Transform Infrared (FT-IR) and mass spectroscopy to confirm their structures and from that analysis, the compounds were identified as two new compounds naming (-)-5,8-dihydroxyjatrophan-3-one (1) and (+)-14,16,17-trihydroxykauran-1-on (2) with total weight 4.9 mg and 4.5 mg respectively. This two compound were reported for this time on this genus.

Original languageMalay
Pages (from-to)64-71
Number of pages8
JournalMalaysian Journal of Analytical Sciences
Volume22
Issue number1
DOIs
Publication statusPublished - 1 Feb 2018

Fingerprint

Diterpenes
Complex Mixtures
Thin layer chromatography
Column chromatography
Chemical compounds
Chromatography
Methanol
Fourier transforms
Nuclear magnetic resonance
Spectroscopy
Vacuum
Infrared radiation
Temperature

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Diterpenoid-diterpenoid terbaharu daripada akar Croton hirtus (Euphorbiaceae). / Rosandy, Andi Rifki; Azman, Anis Asmi; Mohd. Khalid, Rozida; Othaman, Rizafizah; Mat Lazim, Mohamad Azwani Shah; Choudary, Iqbal M.; Syah, Yana Maulana; Latip, Jalifah; Said, Ikram Md; Abu Bakar, Muntaz.

In: Malaysian Journal of Analytical Sciences, Vol. 22, No. 1, 01.02.2018, p. 64-71.

Research output: Contribution to journalArticle

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AU - Othaman, Rizafizah

AU - Mat Lazim, Mohamad Azwani Shah

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AU - Syah, Yana Maulana

AU - Latip, Jalifah

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AU - Abu Bakar, Muntaz

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