Neuroimaging features of tuberculous meningitis

Muda Sobri, J. S. Merican, M. Nordiyana, S. Valarmathi, S. A. Al-Edrus

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Tuberculous meningitis leads to a high mortality rate. However, it responds well to chemotherapy if the treatment is started early. Neuroimaging is one of the most important initial investigations. There were 42 patients diagnosed with tuberculous meningitis in Kuala Lumpur Hospital based on clinical criteria, cerebrospinal fluid anaylsis and response to anti-tuberculous treatment over a 7 year period. Relevant information was obtained from patients medical case notes and neuroimaging findings were evaluated. Male to female ratio was 3:1. The three major ethnics and the immigrant groups in Malaysia were represented in this study. The majority of the cases involved the Malays followed by immigrants, Chinese and Indians. The patients' age ranged from 18 to 62 years old with the mean age of 34.4 years. There were 95.2% (n = 40) of patients who presented with various neuroimaging abnormalities and only 2 (4.8%) patients had normal neuroimaging findings. Hydrocephalus and meningeal enhancement were the two commonest neuroimaging features. Other features include infarction, enhancing lesion, tuberculoma, abcess, oedema and calcification. Contrasted CT scan is an adequate neuroimaging tool to unmask abnormal findings in tuberculous meningitis.

Original languageEnglish
Pages (from-to)36-40
Number of pages5
JournalMedical Journal of Malaysia
Volume61
Issue number1
Publication statusPublished - Mar 2006
Externally publishedYes

Fingerprint

Meningeal Tuberculosis
Neuroimaging
Tuberculoma
Malaysia
Hydrocephalus
Ethnic Groups
Infarction
Cerebrospinal Fluid
Edema
Drug Therapy
Mortality
Therapeutics

Keywords

  • Neuroimaging
  • Tuberculous meningitis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Sobri, M., Merican, J. S., Nordiyana, M., Valarmathi, S., & Al-Edrus, S. A. (2006). Neuroimaging features of tuberculous meningitis. Medical Journal of Malaysia, 61(1), 36-40.

Neuroimaging features of tuberculous meningitis. / Sobri, Muda; Merican, J. S.; Nordiyana, M.; Valarmathi, S.; Al-Edrus, S. A.

In: Medical Journal of Malaysia, Vol. 61, No. 1, 03.2006, p. 36-40.

Research output: Contribution to journalArticle

Sobri, M, Merican, JS, Nordiyana, M, Valarmathi, S & Al-Edrus, SA 2006, 'Neuroimaging features of tuberculous meningitis', Medical Journal of Malaysia, vol. 61, no. 1, pp. 36-40.
Sobri M, Merican JS, Nordiyana M, Valarmathi S, Al-Edrus SA. Neuroimaging features of tuberculous meningitis. Medical Journal of Malaysia. 2006 Mar;61(1):36-40.
Sobri, Muda ; Merican, J. S. ; Nordiyana, M. ; Valarmathi, S. ; Al-Edrus, S. A. / Neuroimaging features of tuberculous meningitis. In: Medical Journal of Malaysia. 2006 ; Vol. 61, No. 1. pp. 36-40.
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