Neuregulin-1 (NRG-1) and its susceptibility to schizophrenia: A case-control study and meta-analysis

Han Chern Loh, Pek Yee Tang, Shiau Foon Tee, Tze Jen Chow, Chee Yen Choong, Shen Yang Lim, Hoi Sen Yong

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Neuregulin-1 is widely investigated due to its hypothesised association with schizophrenia. Single-nucleotide polymorphisms rs764059, rs2954041 and rs3924999 were investigated (417 patients with schizophrenia and 429 controls). We failed to demonstrate a significant association between rs2954041 and rs3924999 with schizophrenia in the three ethnic groups studied (Malay, Chinese, and Indian), while rs764059 was found to be monomorphic.

Original languageEnglish
Pages (from-to)186-188
Number of pages3
JournalPsychiatry Research
Volume208
Issue number2
DOIs
Publication statusPublished - 30 Jul 2013

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Neuregulin-1
Meta-Analysis
Case-Control Studies
Schizophrenia
Ethnic Groups
Single Nucleotide Polymorphism

Keywords

  • Malaysian population
  • Meta-analysis
  • NRG-1

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Neuregulin-1 (NRG-1) and its susceptibility to schizophrenia : A case-control study and meta-analysis. / Loh, Han Chern; Tang, Pek Yee; Tee, Shiau Foon; Chow, Tze Jen; Choong, Chee Yen; Lim, Shen Yang; Yong, Hoi Sen.

In: Psychiatry Research, Vol. 208, No. 2, 30.07.2013, p. 186-188.

Research output: Contribution to journalArticle

Loh, Han Chern ; Tang, Pek Yee ; Tee, Shiau Foon ; Chow, Tze Jen ; Choong, Chee Yen ; Lim, Shen Yang ; Yong, Hoi Sen. / Neuregulin-1 (NRG-1) and its susceptibility to schizophrenia : A case-control study and meta-analysis. In: Psychiatry Research. 2013 ; Vol. 208, No. 2. pp. 186-188.
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