Nephrogenic systemic fibrosis in a patient with renal failure demonstrating a "reverse superscan" on bone scintigraphy

Lih Kin Khor, Kong Bing Tan, Hoi Yin Loi, Suat Jin Lu

Research output: Contribution to journalArticle

Abstract

Nephrogenic systemic fibrosis (NSF) has been linked to utilization of gadolinium-based contrast agents in patients with renal impairment. We present a 19-year-old female patient with end-stage renal failure presenting with joint pains and subcutaneous nodules. She had a prior gadolinium-enhanced magnetic resonance angiography when she was 14 years old. Clinical findings revealed firm subcutaneous nodules in both thighs. Whole-body bone scan demonstrates tracer uptake predominantly in the soft tissues and muscles of the extremities with minimal bony uptake. Incisional biopsy of the left thigh nodule revealed features of NSF with a total pathological score of 4, highly consistent with NSF.

Original languageEnglish
JournalClinical Nuclear Medicine
DOIs
Publication statusAccepted/In press - 24 Jan 2013
Externally publishedYes

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Nephrogenic Fibrosing Dermopathy
Radionuclide Imaging
Renal Insufficiency
Gadolinium
Thigh
Bone and Bones
Whole Body Imaging
Magnetic Resonance Angiography
Arthralgia
Contrast Media
Chronic Kidney Failure
Extremities
Kidney
Biopsy
Muscles

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Nephrogenic systemic fibrosis in a patient with renal failure demonstrating a "reverse superscan" on bone scintigraphy. / Khor, Lih Kin; Tan, Kong Bing; Loi, Hoi Yin; Lu, Suat Jin.

In: Clinical Nuclear Medicine, 24.01.2013.

Research output: Contribution to journalArticle

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