Nasopharyngeal carcinoma (NPC) with liver metastasis in pregnancy

Atiqah Farah Zakaria, Azlan Iskandar Ishak, Min Han Kong, Mohd. Razif Mohamad Yunus

Research output: Contribution to journalArticle

Abstract

Introduction: Cancer in pregnancies is the second most common cause of death after trauma in woman of reproductive age and confounds about 0.1 to 0.2% of pregnancies1,2) and rarely nasopharyngeal carcinoma being the aetiology. Objective: This report describes a pregnant woman in which an advanced-stage NPC was diagnosed and managed accordingly with a review of some related literature reviews. Case report: 29 year old Chinese lady was diagnosed with nasopharyngeal carcinoma (NPC) during her third trimester with very short history. She initially presented to us at 34 weeks of pregnancy with a painless right neck swelling and a chronic non-productive cough for one month duration. She was initially thought to have tuberculous lymphadenitis. A routine rigid endoscopic nasopharyngoscope examination revealed a right Fossa of Rosenmuller (FOR) mass. Biopsy of the nasal mass and fine needle aspiration cytology (FNAC) of the neck swelling further confirmed nasopharyngeal carcinoma- non keratinizing type. After discussion with her obstetrician and the patient, she underwent an elective induction of labor at 36 weeks of gestation, and delivered a healthy 2.77 kg baby boy. Computer tomography (CT) neck, thorax and abdomen were performed 2 weeks postpartum. The imaging showed fullness of the right FOR with metastases to right level 2 cervical lymph node along with metastatic deposits in 2 segments of the liver. She was then referred to oncology unit for further management. Conclusion: In conclusion, high index of suspicion is important in detection of NPC even in pregnant ladies with suspicious neck swelling. Method of detecting NPC early in pregnancy is essential in order to give optimize treatment, achieve potential for full recovery and also reduced the adverse risk and complications associated with NPC.

Original languageEnglish
Pages (from-to)584-586
Number of pages3
JournalInternational Medical Journal
Volume23
Issue number5
Publication statusPublished - 2016

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Neoplasm Metastasis
Pregnancy
Liver
Neck
Induced Labor
Lymph Node Tuberculosis
Third Pregnancy Trimester
Fine Needle Biopsy
Nasopharyngeal carcinoma
Nose
Cough
Abdomen
Postpartum Period
Cell Biology
Pregnant Women
Cause of Death
Thorax
Lymph Nodes
History
Tomography

Keywords

  • Metastasis
  • Nasopharyngeal carcinoma
  • Pregnancy

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Nasopharyngeal carcinoma (NPC) with liver metastasis in pregnancy. / Zakaria, Atiqah Farah; Ishak, Azlan Iskandar; Kong, Min Han; Mohamad Yunus, Mohd. Razif.

In: International Medical Journal, Vol. 23, No. 5, 2016, p. 584-586.

Research output: Contribution to journalArticle

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