Nanocrystalline cellulose decorated quantum dots based tyrosinase biosensor for phenol determination

Fariza Aina Abd Manan, Wai Weng Hong, Jaafar Abdullah, Nor Azah Yusof, Ishak Ahmad

Research output: Contribution to journalArticle

Abstract

Novel biosensor architecture based on nanocrystalline cellulose (NCC)/CdS quantum dots (QDs) nanocomposite was developed for phenol determination. This nanocomposite was prepared with slight modification of nanocrystalline cellulose (NCC) with cationic surfactant of cetyltriammonium bromide (CTAB) and further decorated with 3-mercaptopropionic acid (3-MPA) capped CdS QDs. The nanocomposite material was then employed as scaffold for immobilization of tyrosinase enzyme (Tyr). The electrocatalytic response of Tyr/CTAB-NCC/QDs nanocomposite towards phenol was evaluated using differential pulse voltammetry (DPV). The current response obtained is proportional to the concentration of phenol which attributed to the reduction of o-quinone produced at the surface of the modified electrode. Under the optimal conditions, the biosensor exhibits good linearity towards phenol in the concentration range of 5–40 μM (R2 = 0.9904) with sensitivity and limit of detection (LOD) of 0.078 μA/μM and 0.082 μM, respectively.

Original languageEnglish
Pages (from-to)37-46
Number of pages10
JournalMaterials Science and Engineering C
Volume99
DOIs
Publication statusPublished - 1 Jun 2019

Fingerprint

Monophenol Monooxygenase
Phenol
cellulose
bioinstrumentation
Biosensors
Cellulose
phenols
Semiconductor quantum dots
Phenols
Nanocomposites
nanocomposites
quantum dots
Bromides
bromides
3-Mercaptopropionic Acid
Cationic surfactants
quinones
Voltammetry
Scaffolds (biology)
immobilization

Keywords

  • Biosensor
  • Electrochemical
  • Nanocrystalline cellulose
  • Quantum dots
  • Tyrosinase

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Nanocrystalline cellulose decorated quantum dots based tyrosinase biosensor for phenol determination. / Manan, Fariza Aina Abd; Hong, Wai Weng; Abdullah, Jaafar; Yusof, Nor Azah; Ahmad, Ishak.

In: Materials Science and Engineering C, Vol. 99, 01.06.2019, p. 37-46.

Research output: Contribution to journalArticle

Manan, Fariza Aina Abd ; Hong, Wai Weng ; Abdullah, Jaafar ; Yusof, Nor Azah ; Ahmad, Ishak. / Nanocrystalline cellulose decorated quantum dots based tyrosinase biosensor for phenol determination. In: Materials Science and Engineering C. 2019 ; Vol. 99. pp. 37-46.
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