Nano-constructed carriers loaded with antioxidant: Boon for cardiovascular system

Ashay Jain, Prashant Kesharwani, Neeraj Kumar Garg, Atul Jain, Pradip Nirbhavane, Nitin Dwivedi, Sanjeev Banerjee, Arun K. Iyer, Mohd Cairul Iqbal Mohd Amin

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

In the last couple of decades antioxidant agents have entered the health market as an easy and attractive means of managing diseases. These agents are of enormous interest for an increasingly health-concerned society, and may be particularly relevant for prophylaxis of a number of diseases i.e. arthritis, cancer, metabolic and cardiovascular diseases, osteoporosis, cataracts, brain disorders, etc. Antioxidants are also favorable to vascular healthiness and symbolize useful compounds because they are able to diminish overall cardiovascular risk by acting analogous to first line therapy or as adjuvants in case of failure or in situations where first line therapy cannot be used. Furthermore, well-designed trials are indeed needed to improve the therapeutic efficacy and health benefits of antioxidants. Numerous in vivo proof-of-concepts studies are offered to underline the feasibility of nanostructure system in order to optimizing the delivery of cardiovascular drugs. The present review highlights the recent approaches for management of cardiovascular disease using different vesicular and particulate carriers, including liposomes, nanoparticles, and nanoemulsions, with a primary emphasis on those which are expected to enhance the antioxidants level.

Original languageEnglish
Pages (from-to)4456-4464
Number of pages9
JournalCurrent Pharmaceutical Design
Volume21
Issue number30
Publication statusPublished - 1 Sep 2015

Fingerprint

Cardiovascular System
Antioxidants
Cardiovascular Diseases
Cardiovascular Agents
Nanostructures
Metabolic Diseases
Health
Brain Diseases
Insurance Benefits
Liposomes
Nanoparticles
Cataract
Osteoporosis
Arthritis
Blood Vessels
Therapeutics
Neoplasms

Keywords

  • Antioxidants
  • Cardiovascular diseases
  • Liposomes
  • Nanoemulsions
  • Nanoparticles

ASJC Scopus subject areas

  • Drug Discovery
  • Pharmacology

Cite this

Jain, A., Kesharwani, P., Garg, N. K., Jain, A., Nirbhavane, P., Dwivedi, N., ... Mohd Amin, M. C. I. (2015). Nano-constructed carriers loaded with antioxidant: Boon for cardiovascular system. Current Pharmaceutical Design, 21(30), 4456-4464.

Nano-constructed carriers loaded with antioxidant : Boon for cardiovascular system. / Jain, Ashay; Kesharwani, Prashant; Garg, Neeraj Kumar; Jain, Atul; Nirbhavane, Pradip; Dwivedi, Nitin; Banerjee, Sanjeev; Iyer, Arun K.; Mohd Amin, Mohd Cairul Iqbal.

In: Current Pharmaceutical Design, Vol. 21, No. 30, 01.09.2015, p. 4456-4464.

Research output: Contribution to journalArticle

Jain, A, Kesharwani, P, Garg, NK, Jain, A, Nirbhavane, P, Dwivedi, N, Banerjee, S, Iyer, AK & Mohd Amin, MCI 2015, 'Nano-constructed carriers loaded with antioxidant: Boon for cardiovascular system', Current Pharmaceutical Design, vol. 21, no. 30, pp. 4456-4464.
Jain A, Kesharwani P, Garg NK, Jain A, Nirbhavane P, Dwivedi N et al. Nano-constructed carriers loaded with antioxidant: Boon for cardiovascular system. Current Pharmaceutical Design. 2015 Sep 1;21(30):4456-4464.
Jain, Ashay ; Kesharwani, Prashant ; Garg, Neeraj Kumar ; Jain, Atul ; Nirbhavane, Pradip ; Dwivedi, Nitin ; Banerjee, Sanjeev ; Iyer, Arun K. ; Mohd Amin, Mohd Cairul Iqbal. / Nano-constructed carriers loaded with antioxidant : Boon for cardiovascular system. In: Current Pharmaceutical Design. 2015 ; Vol. 21, No. 30. pp. 4456-4464.
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