Myocardial infarction false alarm

Initial electrocardiogram and cardiac enzymes

Esha Das Gupta, Sakthiswary Rajalingham

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: The objectives of this study were to determine the incidence of a myocardial infarction "false alarm" and evaluate the efficacy of the initial electrocardiogram and cardiac enzymes in diagnosing myocardial infarction in Malaysia. Methods: We recruited patients who were admitted with suspected myocardial infarction from June to August 2008. The medical records of these patients were reviewed for the initial electrocardiogram, initial cardiac enzyme levels (creatinine kinase-MB and troponin T), and the final diagnosis upon discharge. The subjects were stratified into 2 groups: true myocardial infarction, and false alarm. Results: 125 patients were enrolled in this study. Following admission and further evaluation, the diagnosis was revised from myocardial infarction to other medical conditions in 48 (38.4%) patients. The sensitivity and specificity of the initial ischemic electrocardiographic changes were 54.5% and 70.8%, respectively. Raised cardiac enzymes had a sensitivity of 44.3% and specificity of 95.8%. Conclusion: A significant proportion of patients in Malaysia are admitted with a false-alarm myocardial infarction. The efficacy of the electrocardiogram in diagnosing myocardial infarction in Malaysia was comparable to the findings of Western studies, but the cardiac enzymes had a much lower sensitivity.

Original languageEnglish
Pages (from-to)397-401
Number of pages5
JournalAsian Cardiovascular and Thoracic Annals
Volume22
Issue number4
DOIs
Publication statusPublished - 2014

Fingerprint

Electrocardiography
Myocardial Infarction
Enzymes
Malaysia
Sensitivity and Specificity
Troponin T
Medical Records
Creatinine
Phosphotransferases
Incidence

Keywords

  • Biological markers
  • creatine kinase
  • electrocardiography
  • malaysia
  • MB form
  • myocardial infarction
  • troponin T

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pulmonary and Respiratory Medicine
  • Medicine(all)

Cite this

Myocardial infarction false alarm : Initial electrocardiogram and cardiac enzymes. / Gupta, Esha Das; Rajalingham, Sakthiswary.

In: Asian Cardiovascular and Thoracic Annals, Vol. 22, No. 4, 2014, p. 397-401.

Research output: Contribution to journalArticle

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