Myeloid Sarcoma of Temporal Bone: A Rare Manifestation of Relapse Acute Myeloid Leukemia

Bee See Goh, Chian Ling Tang, Geok Chin Tan

Research output: Contribution to journalArticle

Abstract

Myeloid sarcoma is a rare malignant extramedullary neoplasm of myeloid precursor cells. This disorder may occur in concomitance with or precede development of acute or chronic myeloid leukemia. Sometimes, it is the initial manifestation of relapse in a previously treated acute myeloid leukemia. We report a case of 11 years old boy with acute myeloid leukemia in remission state, presented with short history of right otalgia associated with facial nerve palsy. Diagnosis of right acute mastoiditis with facial nerve palsy as complication of acute otitis media was made initially. Patient underwent simple cortical mastoidectomy but histopathology from soft tissue that was sent revealed diagnosis of myeloid sarcoma. A leukemic relapse was confirmed by paediatric oncologist through bone marrow biopsy. Chemotherapy was commenced but patient responded poorly to the treatment.

Original languageEnglish
Pages (from-to)1-4
Number of pages4
JournalIndian Journal of Otolaryngology and Head and Neck Surgery
DOIs
Publication statusAccepted/In press - 12 Dec 2015

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Myeloid Sarcoma
Temporal Bone
Acute Myeloid Leukemia
Facial Paralysis
Facial Nerve
Recurrence
Earache
Mastoiditis
Otitis Media
Myeloid Cells
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Bone Marrow
Pediatrics
Biopsy
Drug Therapy
Neoplasms
Therapeutics

Keywords

  • Acute mastoiditis
  • Acute myeloid leukemia
  • Facial nerve palsy
  • Myeloid sarcoma

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Surgery

Cite this

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abstract = "Myeloid sarcoma is a rare malignant extramedullary neoplasm of myeloid precursor cells. This disorder may occur in concomitance with or precede development of acute or chronic myeloid leukemia. Sometimes, it is the initial manifestation of relapse in a previously treated acute myeloid leukemia. We report a case of 11 years old boy with acute myeloid leukemia in remission state, presented with short history of right otalgia associated with facial nerve palsy. Diagnosis of right acute mastoiditis with facial nerve palsy as complication of acute otitis media was made initially. Patient underwent simple cortical mastoidectomy but histopathology from soft tissue that was sent revealed diagnosis of myeloid sarcoma. A leukemic relapse was confirmed by paediatric oncologist through bone marrow biopsy. Chemotherapy was commenced but patient responded poorly to the treatment.",
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