Mosquitocidal and oviposition repellent activities of the extracts of seaweed Bryopsis pennata on Aedes aegypti and Aedes albopictus

Ke Xin Yu, Ching Lee Wong, Rohani Ahmad, Ibrahim Jantan

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The ever-increasing threat from infectious diseases and the development of insecticide resistance in mosquito populations drive the global search for new natural insecticides. The aims of this study were to evaluate the mosquitocidal activity of the extracts of seaweed Bryopsis pennata against dengue vectors Aedes aegypti and Aedes albopictus, and determine the seaweed's toxic effect on brine shrimp nauplii (as a non-target organism). In addition, the chemical compositions of the active larvicidal extract and fraction were analyzed by using liquid chromatography-mass spectrometry (LC-MS). Chloroform extract exhibited strong ovicidal activity (with LC<inf>50</inf> values of 229.3 and 250.5 μg/mL) and larvicidal activity against Ae. aegypti and Ae. albopictus. The larvicidal potential of chloroform extract was further ascertained when its A7 fraction exhibited strong toxic effect against Ae. aegypti (LC<inf>50</inf> = 4.7 μg/mL) and Ae. albopictus (LC<inf>50</inf> = 5.3 μg/mL). LC-MS analysis of the chloroform extract gave a tentative identification of 13 compounds; Bis-(3-oxoundecyl) tetrasulfide was identified as the major compound in A7 fraction. Methanol extract showed strong repellent effect against female oviposition, along with weak adulticidal activity against mosquito and weak toxicity against brine shrimp nauplii. The mosquitocidal results of B. pennata suggest further investigation for the development of effective insecticide.

Original languageEnglish
Article number14082
Pages (from-to)14082-14102
Number of pages21
JournalMolecules
Volume20
Issue number8
DOIs
Publication statusPublished - 1 Aug 2015

Fingerprint

seaweeds
Seaweed
Oviposition
Aedes
insecticides
Insecticides
Chloroform
Artemia
Poisons
chloroform
Liquid chromatography
Culicidae
Liquid Chromatography
Mass spectrometry
Mass Spectrometry
liquid chromatography
Insecticide Resistance
mass spectroscopy
Dengue
Communicable Diseases

Keywords

  • Bis-(3-oxoundecyl) tetrasulfide
  • Dengue vector
  • Insecticide
  • Larvicidal
  • Ovicidal

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Mosquitocidal and oviposition repellent activities of the extracts of seaweed Bryopsis pennata on Aedes aegypti and Aedes albopictus. / Yu, Ke Xin; Wong, Ching Lee; Ahmad, Rohani; Jantan, Ibrahim.

In: Molecules, Vol. 20, No. 8, 14082, 01.08.2015, p. 14082-14102.

Research output: Contribution to journalArticle

@article{11e4c482614541d596d390e86fbd9285,
title = "Mosquitocidal and oviposition repellent activities of the extracts of seaweed Bryopsis pennata on Aedes aegypti and Aedes albopictus",
abstract = "The ever-increasing threat from infectious diseases and the development of insecticide resistance in mosquito populations drive the global search for new natural insecticides. The aims of this study were to evaluate the mosquitocidal activity of the extracts of seaweed Bryopsis pennata against dengue vectors Aedes aegypti and Aedes albopictus, and determine the seaweed's toxic effect on brine shrimp nauplii (as a non-target organism). In addition, the chemical compositions of the active larvicidal extract and fraction were analyzed by using liquid chromatography-mass spectrometry (LC-MS). Chloroform extract exhibited strong ovicidal activity (with LC50 values of 229.3 and 250.5 μg/mL) and larvicidal activity against Ae. aegypti and Ae. albopictus. The larvicidal potential of chloroform extract was further ascertained when its A7 fraction exhibited strong toxic effect against Ae. aegypti (LC50 = 4.7 μg/mL) and Ae. albopictus (LC50 = 5.3 μg/mL). LC-MS analysis of the chloroform extract gave a tentative identification of 13 compounds; Bis-(3-oxoundecyl) tetrasulfide was identified as the major compound in A7 fraction. Methanol extract showed strong repellent effect against female oviposition, along with weak adulticidal activity against mosquito and weak toxicity against brine shrimp nauplii. The mosquitocidal results of B. pennata suggest further investigation for the development of effective insecticide.",
keywords = "Bis-(3-oxoundecyl) tetrasulfide, Dengue vector, Insecticide, Larvicidal, Ovicidal",
author = "Yu, {Ke Xin} and Wong, {Ching Lee} and Rohani Ahmad and Ibrahim Jantan",
year = "2015",
month = "8",
day = "1",
doi = "10.3390/molecules200814082",
language = "English",
volume = "20",
pages = "14082--14102",
journal = "Molecules",
issn = "1420-3049",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "8",

}

TY - JOUR

T1 - Mosquitocidal and oviposition repellent activities of the extracts of seaweed Bryopsis pennata on Aedes aegypti and Aedes albopictus

AU - Yu, Ke Xin

AU - Wong, Ching Lee

AU - Ahmad, Rohani

AU - Jantan, Ibrahim

PY - 2015/8/1

Y1 - 2015/8/1

N2 - The ever-increasing threat from infectious diseases and the development of insecticide resistance in mosquito populations drive the global search for new natural insecticides. The aims of this study were to evaluate the mosquitocidal activity of the extracts of seaweed Bryopsis pennata against dengue vectors Aedes aegypti and Aedes albopictus, and determine the seaweed's toxic effect on brine shrimp nauplii (as a non-target organism). In addition, the chemical compositions of the active larvicidal extract and fraction were analyzed by using liquid chromatography-mass spectrometry (LC-MS). Chloroform extract exhibited strong ovicidal activity (with LC50 values of 229.3 and 250.5 μg/mL) and larvicidal activity against Ae. aegypti and Ae. albopictus. The larvicidal potential of chloroform extract was further ascertained when its A7 fraction exhibited strong toxic effect against Ae. aegypti (LC50 = 4.7 μg/mL) and Ae. albopictus (LC50 = 5.3 μg/mL). LC-MS analysis of the chloroform extract gave a tentative identification of 13 compounds; Bis-(3-oxoundecyl) tetrasulfide was identified as the major compound in A7 fraction. Methanol extract showed strong repellent effect against female oviposition, along with weak adulticidal activity against mosquito and weak toxicity against brine shrimp nauplii. The mosquitocidal results of B. pennata suggest further investigation for the development of effective insecticide.

AB - The ever-increasing threat from infectious diseases and the development of insecticide resistance in mosquito populations drive the global search for new natural insecticides. The aims of this study were to evaluate the mosquitocidal activity of the extracts of seaweed Bryopsis pennata against dengue vectors Aedes aegypti and Aedes albopictus, and determine the seaweed's toxic effect on brine shrimp nauplii (as a non-target organism). In addition, the chemical compositions of the active larvicidal extract and fraction were analyzed by using liquid chromatography-mass spectrometry (LC-MS). Chloroform extract exhibited strong ovicidal activity (with LC50 values of 229.3 and 250.5 μg/mL) and larvicidal activity against Ae. aegypti and Ae. albopictus. The larvicidal potential of chloroform extract was further ascertained when its A7 fraction exhibited strong toxic effect against Ae. aegypti (LC50 = 4.7 μg/mL) and Ae. albopictus (LC50 = 5.3 μg/mL). LC-MS analysis of the chloroform extract gave a tentative identification of 13 compounds; Bis-(3-oxoundecyl) tetrasulfide was identified as the major compound in A7 fraction. Methanol extract showed strong repellent effect against female oviposition, along with weak adulticidal activity against mosquito and weak toxicity against brine shrimp nauplii. The mosquitocidal results of B. pennata suggest further investigation for the development of effective insecticide.

KW - Bis-(3-oxoundecyl) tetrasulfide

KW - Dengue vector

KW - Insecticide

KW - Larvicidal

KW - Ovicidal

UR - http://www.scopus.com/inward/record.url?scp=84941249085&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84941249085&partnerID=8YFLogxK

U2 - 10.3390/molecules200814082

DO - 10.3390/molecules200814082

M3 - Article

VL - 20

SP - 14082

EP - 14102

JO - Molecules

JF - Molecules

SN - 1420-3049

IS - 8

M1 - 14082

ER -