Mosquito repellent activity of the methanol extracts of some ascidian species

Zeti Azura Mohamed Hussein, Ibrahim Jantan, Alma Awaludin, Nazni Wasi Ahmad

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The methanol extracts of seven marine ascidian species (Clavelina picta, Eudistoma obscuratum, Atriolum robustum, Didemnum sp., D. molle, Phallusia sp. and Aplidium sp.) from Malaysia were investigated for their repellency effects against four vector mosquitoes (Anopheles maculatus, Aedes aegypti, Ae. albopictus and Culex quinquefasciatus). Mosquito repellent activity was assessed by using the test cage described in the American Society for Testing and Materials standard E951-83. The extracts showed a significant degree of repellency against the mosquitoes with ED50 values ranging from 0.0008 to 0.0746 mg cm-2. The repellency effects were dose-dependent and selective as the ED50 values showed variation towards the various mosquitoes. Amongst these, the extract of Didemnum sp., with an ED50 of 0.0008 mg cm-2 against An. maculatus, was the most effective, comparable to the value obtained with the standard repellent, deet.

Original languageEnglish
Pages (from-to)358-361
Number of pages4
JournalPharmaceutical Biology
Volume40
Issue number5
DOIs
Publication statusPublished - Aug 2002

Fingerprint

Urochordata
Ascidiacea
repellents
Culicidae
Methanol
Anopheles maculatus
methanol
extracts
Materials Testing
Culex
Anopheles
Aedes
Malaysia
deet
Culex quinquefasciatus
Testing
Aedes aegypti
cages
testing
dosage

Keywords

  • Aedes aegypti
  • Aedes albopictus
  • Anopheles maculatus
  • Ascidians
  • Culex quinquefasciatus
  • Methanol extracts
  • Mosquito repellent
  • Tunicates

ASJC Scopus subject areas

  • Plant Science
  • Medical Laboratory Technology
  • Clinical Biochemistry
  • Pharmacology

Cite this

Mosquito repellent activity of the methanol extracts of some ascidian species. / Mohamed Hussein, Zeti Azura; Jantan, Ibrahim; Awaludin, Alma; Ahmad, Nazni Wasi.

In: Pharmaceutical Biology, Vol. 40, No. 5, 08.2002, p. 358-361.

Research output: Contribution to journalArticle

Mohamed Hussein, Zeti Azura ; Jantan, Ibrahim ; Awaludin, Alma ; Ahmad, Nazni Wasi. / Mosquito repellent activity of the methanol extracts of some ascidian species. In: Pharmaceutical Biology. 2002 ; Vol. 40, No. 5. pp. 358-361.
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