Molecular existence of mature odontoblast and osteoblast cells in adult human pulp tissues

A. Eni Juliana, Shahrul Hisham Zainal Ariffin, Rohaya Megat Abdul Wahab, Nik Marzuki Sidik

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The dental pulp tissue is essential in dentine development. The existence of Dental Pulp Stem Cells (DPSCs), i.e., osteoblast and odontoblast are to assist in dentine repair and tooth regeneration. The existence of osteoblast that secreted bone matrix directly from pulp tissue has not been reported. The purpose of this study is to determine the existence of odontoblast and osteoblast cells excavated directly from pulp tissues by using molecular markers. The isolated RNA expressing two gene markers, i.e., dentin sialophosphoprotein and osteocalcin which were secreted by odontoblast and osteoblast cells, respectively. The expression of dentin sialophosphoprotein and osteocalcin demonstrated that both odontoblast and osteoblast cells exist in adult human pulp tissues.

Original languageEnglish
Pages (from-to)36-44
Number of pages9
JournalAsian Journal of Biochemistry
Volume4
Issue number2
DOIs
Publication statusPublished - 2009

Fingerprint

Odontoblasts
Osteoblasts
Pulp
Tissue
Dental Pulp
Osteocalcin
Dentin
Bone Matrix
Stem cells
Regeneration
Tooth
Bone
Repair
Stem Cells
Genes
RNA

Keywords

  • Dentin sialophosphoprotein
  • Odontoblast
  • Osteoblast
  • Osteocalcin
  • Pulp tissue

ASJC Scopus subject areas

  • Biochemistry
  • Biochemistry, medical

Cite this

Molecular existence of mature odontoblast and osteoblast cells in adult human pulp tissues. / Eni Juliana, A.; Zainal Ariffin, Shahrul Hisham; Megat Abdul Wahab, Rohaya; Sidik, Nik Marzuki.

In: Asian Journal of Biochemistry, Vol. 4, No. 2, 2009, p. 36-44.

Research output: Contribution to journalArticle

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