Microscopic and transition investigation on the effect of cholesterol in AOT solution

Chun Yuan Tan, Khoo Kok Siong Kok Siong, Shahidan Radiman, Irman Abdul Rahman, Nur Farhana Bt Amari

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The effects of cholesterol on vesicle were studied in this paper. Anionic bis-(2-ethylhexyl)sulfosuccinate (AOT) surfactant and brine water were used to prepare the vesicle. Effects on vesicle size were observed using polarized light microscopy (PLM) and dynamic light scattering (DLS), whereas thermal properties were measured using differential scanning calorimeter (DSC). The results were compared among AOT solutions before and after the addition of various amounts of cholesterol, showing difference in vesicle size, microscopy scale, hydrodynamic diameter, and main transition temperature (Tm). These changes were attributed to the entrapment of cholesterol molecules in the hydrophobic part of vesicles.

Original languageEnglish
Pages (from-to)156-159
Number of pages4
JournalJournal of Molecular Liquids
Volume178
DOIs
Publication statusPublished - Feb 2013

Fingerprint

Cholesterol
cholesterol
microscopy
entrapment
Dynamic light scattering
Light polarization
Calorimeters
Surface-Active Agents
polarized light
Superconducting transition temperature
Optical microscopy
calorimeters
Microscopic examination
Surface active agents
light scattering
Thermodynamic properties
Hydrodynamics
thermodynamic properties
transition temperature
surfactants

Keywords

  • Cholesterol
  • Dynamic light scattering
  • Main transition temperature
  • Polarized light microscopy
  • Size distribution
  • Sodium bis-(2-ethylhexyl)sulfosuccinate (AOT)

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Spectroscopy
  • Condensed Matter Physics
  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Materials Chemistry

Cite this

Microscopic and transition investigation on the effect of cholesterol in AOT solution. / Tan, Chun Yuan; Kok Siong, Khoo Kok Siong; Radiman, Shahidan; Abdul Rahman, Irman; Bt Amari, Nur Farhana.

In: Journal of Molecular Liquids, Vol. 178, 02.2013, p. 156-159.

Research output: Contribution to journalArticle

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