MicroRNA and transcription factor: Key players in plant regulatory network

Abdul F.A. Samad, Muhammad Sajad, Nazaruddin Nazaruddin, Izzat A. Fauzi, Abdul Munir Abd. Murad, Zamri Zainal, Ismanizan Ismail

Research output: Contribution to journalReview article

55 Citations (Scopus)

Abstract

Recent achievements in plant microRNA (miRNA), a large class of small and non-coding RNAs, are very exciting. A wide array of techniques involving forward genetic, molecular cloning, bioinformatic analysis, and the latest technology, deep sequencing have greatly advanced miRNA discovery. A tiny miRNA sequence has the ability to target single/multiple mRNA targets. Most of the miRNA targets are transcription factors (TFs) which have paramount importance in regulating the plant growth and development. Various families of TFs, which have regulated a range of regulatory networks, may assist plants to grow under normal and stress environmental conditions. This present review focuses on the regulatory relationships between miRNAs and different families of TFs like; NF-Y, MYB, AP2, TCP, WRKY, NAC, GRF, and SPL. For instance NF-Y play important role during drought tolerance and flower development, MYB are involved in signal transduction and biosynthesis of secondary metabolites, AP2 regulate the floral development and nodule formation, TCP direct leaf development and growth hormones signaling. WRKY have known roles in multiple stress tolerances, NAC regulate lateral root formation, GRF are involved in root growth, flower, and seed development, and SPL regulate plant transition from juvenile to adult. We also studied the relation between miRNAs and TFs by consolidating the research findings from different plant species which will help plant scientists in understanding the mechanism of action and interaction between these regulators in the plant growth and development under normal and stress environmental conditions.

Original languageEnglish
Article number565
JournalFrontiers in Plant Science
Volume8
DOIs
Publication statusPublished - 12 Apr 2017

Fingerprint

microRNA
transcription factors
flowering
plant development
growth and development
plant growth
environmental factors
leaf development
seed development
bioinformatics
drought tolerance
stress tolerance
somatotropin
secondary metabolites
signal transduction
molecular cloning
mechanism of action
root growth
biosynthesis
methodology

Keywords

  • MiRNAs
  • Plant development
  • Plant regulators
  • Stress response
  • Transcription factors

ASJC Scopus subject areas

  • Plant Science

Cite this

MicroRNA and transcription factor : Key players in plant regulatory network. / Samad, Abdul F.A.; Sajad, Muhammad; Nazaruddin, Nazaruddin; Fauzi, Izzat A.; Abd. Murad, Abdul Munir; Zainal, Zamri; Ismail, Ismanizan.

In: Frontiers in Plant Science, Vol. 8, 565, 12.04.2017.

Research output: Contribution to journalReview article

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