Metastases to the oral region from pleural mesothelioma: Clinicopathologic review

Suraya Hani Mohd. Sinon, Alison M. Rich, Haizal M. Hussaini, Han Seung Yoon, Norman A. Firth, Gregory J. Seymour

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background: Malignant mesothelioma is a rare neoplasm that usually develops after exposure to asbestos and particularly involves the pleural cavity. It has a poor prognosis with aggressive local invasion and metastatic spread. Methods: The literature relating to malignant mesothelioma metastatic to the oral region was reviewed. Results: In all, 14 cases of malignant mesothelioma metastatic to the oral cavity were found. All were from pleural mesotheliomas, the tongue was the most common site of metastasis (8/14), and most metastases (9/13) were of the epithelioid type. The newly reported case is only the second report of a mesothelioma metastasizing to the buccal mucosa. It showed strong immunopositivity for keratin markers, vimentin, calretinin, and Wilms tumor product-1. Conclusion:s The incidence of mesothelioma is predicted to continue to increase for at least another decade. Clinicians and pathologists should be aware of this lesion and its propensity to metastasize to the oral cavity.

Original languageEnglish
Pages (from-to)599-604
Number of pages6
JournalHead and Neck
Volume35
Issue number4
DOIs
Publication statusPublished - Apr 2013
Externally publishedYes

Fingerprint

Mesothelioma
Neoplasm Metastasis
Mouth
Calbindin 2
Pleural Cavity
Wilms Tumor
Asbestos
Mouth Mucosa
Vimentin
Keratins
Tongue
Incidence
Malignant Mesothelioma
Neoplasms

Keywords

  • malignant mesothelioma
  • oral mucosal metastasis

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Mohd. Sinon, S. H., Rich, A. M., Hussaini, H. M., Yoon, H. S., Firth, N. A., & Seymour, G. J. (2013). Metastases to the oral region from pleural mesothelioma: Clinicopathologic review. Head and Neck, 35(4), 599-604. https://doi.org/10.1002/hed.21942

Metastases to the oral region from pleural mesothelioma : Clinicopathologic review. / Mohd. Sinon, Suraya Hani; Rich, Alison M.; Hussaini, Haizal M.; Yoon, Han Seung; Firth, Norman A.; Seymour, Gregory J.

In: Head and Neck, Vol. 35, No. 4, 04.2013, p. 599-604.

Research output: Contribution to journalArticle

Mohd. Sinon, SH, Rich, AM, Hussaini, HM, Yoon, HS, Firth, NA & Seymour, GJ 2013, 'Metastases to the oral region from pleural mesothelioma: Clinicopathologic review', Head and Neck, vol. 35, no. 4, pp. 599-604. https://doi.org/10.1002/hed.21942
Mohd. Sinon, Suraya Hani ; Rich, Alison M. ; Hussaini, Haizal M. ; Yoon, Han Seung ; Firth, Norman A. ; Seymour, Gregory J. / Metastases to the oral region from pleural mesothelioma : Clinicopathologic review. In: Head and Neck. 2013 ; Vol. 35, No. 4. pp. 599-604.
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