Metabolic engineering and synthetic biology

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

In the modern era of next-generation genomics and Fourth Industrial Revolution, there is a growing demand for translational research that brings about not only impactful research but also potential commercialisation of R- and D-based products. Advancement of metabolic engineering and synthetic biology has put forward a viable and innovative biotechnological platform for bioproduct development especially using microbial chassis. In this chapter, readers will be introduced on the concepts of metabolic engineering, synthetic biology and microbial chassis and the applications of these biological engineering (BioE) components in the advancement of industrial and agricultural biotechnology. Main strategies in employing BioE platform are discussed especially for waste bioconversion and value-added product development. More importantly, this chapter will also discuss current endeavours in integrating systems and synthetic biology for microbial production of natural products by introducing flavonoid biosynthesis genes of Polygonum minus, a medicinally important tropical plant in engineered yeast.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Pages81-95
Number of pages15
DOIs
Publication statusPublished - 1 Jan 2018

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1102
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Fingerprint

Synthetic Biology
Metabolic engineering
Metabolic Engineering
Bioengineering
Chassis
Polygonum
Bioconversion
Translational Medical Research
Systems Biology
Biosynthesis
Biotechnology
Genomics
Biological Products
Flavonoids
Product development
Yeast
Genes
Yeasts
Research

Keywords

  • Biological engineering
  • Industrial biotechnology
  • Metabolic engineering
  • Microbial chassis
  • Synthetic biology

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Ahmad Bazli, R. (2018). Metabolic engineering and synthetic biology. In Advances in Experimental Medicine and Biology (pp. 81-95). (Advances in Experimental Medicine and Biology; Vol. 1102). Springer New York LLC. https://doi.org/10.1007/978-3-319-98758-3_6

Metabolic engineering and synthetic biology. / Ahmad Bazli, Ramzi.

Advances in Experimental Medicine and Biology. Springer New York LLC, 2018. p. 81-95 (Advances in Experimental Medicine and Biology; Vol. 1102).

Research output: Chapter in Book/Report/Conference proceedingChapter

Ahmad Bazli, R 2018, Metabolic engineering and synthetic biology. in Advances in Experimental Medicine and Biology. Advances in Experimental Medicine and Biology, vol. 1102, Springer New York LLC, pp. 81-95. https://doi.org/10.1007/978-3-319-98758-3_6
Ahmad Bazli R. Metabolic engineering and synthetic biology. In Advances in Experimental Medicine and Biology. Springer New York LLC. 2018. p. 81-95. (Advances in Experimental Medicine and Biology). https://doi.org/10.1007/978-3-319-98758-3_6
Ahmad Bazli, Ramzi. / Metabolic engineering and synthetic biology. Advances in Experimental Medicine and Biology. Springer New York LLC, 2018. pp. 81-95 (Advances in Experimental Medicine and Biology).
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