Mammalian sperm fertility related proteins

Ali Ashrafzadeh, Saiful Anuar Karsani, Sheila Nathan

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Infertility is an important aspect of human and animal reproduction and still presents with much etiological ambiguity. As fifty percent of infertility is related to the male partner, molecular investigations on sperm and seminal plasma can lead to new knowledge on male infertility. Several comparisons between fertile and infertile human and other species sperm proteome have shown the existence of potential fertility markers. These proteins have been categorized into energy related, structural and other functional proteins which play a major role in sperm motility, capacitation and sperm-oocyte binding. The data from these studies show the impact of sperm proteome studies on identifying different valuable markers for fertility screening. In this article, we review recent development in unraveling sperm fertility related proteins.

Original languageEnglish
Pages (from-to)1649-1657
Number of pages9
JournalInternational Journal of Medical Sciences
Volume10
Issue number12
DOIs
Publication statusPublished - 23 Sep 2013

Fingerprint

Fertility
Spermatozoa
Proteome
Proteins
Infertility
Sperm Capacitation
Sperm Motility
Male Infertility
Semen
Oocytes
Reproduction

Keywords

  • Fertility
  • Infertility
  • Protein
  • Proteomics
  • Sperm

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Mammalian sperm fertility related proteins. / Ashrafzadeh, Ali; Karsani, Saiful Anuar; Nathan, Sheila.

In: International Journal of Medical Sciences, Vol. 10, No. 12, 23.09.2013, p. 1649-1657.

Research output: Contribution to journalArticle

Ashrafzadeh, Ali ; Karsani, Saiful Anuar ; Nathan, Sheila. / Mammalian sperm fertility related proteins. In: International Journal of Medical Sciences. 2013 ; Vol. 10, No. 12. pp. 1649-1657.
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