Macular retinal sensitivity using MP-1 in healthy Malaysian subjects of different ages

Siti Aishah Ismail, Sharanjeet Kaur Malkeet Singh, Haliza Abdul Mutalib, Nor Fariza Ngah

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Purpose To determine the influence of age and gender on macular sensitivity to light in healthy subjects of 4 age groups using the MP-1 microperimeter. Methods A prospective study was carried out on 50 healthy subjects (age range: 18-60 years) divided into 4 age groups; 18-30 years, 31-40 years, 41-50 years and 51-60 years. Full-threshold microperimetry of the central 10° of retina was performed utilizing 32 points with the MP-1. Macula area was divided into four quadrants, which were superior nasal (SN), inferior nasal (IN), inferior temporal (IT) and superior temporal (ST). Results Total mean sensitivity at 10° for age groups 18-30 years, 31-40 years, 41-50 years and 51-60 years were 19.46 ± 0.30, 19.40 ± 0.39, 19.47 ± 0.35 and 18.73 ± 0.75 (dB), respectively. There was a significant difference in total mean retinal sensitivity at 10° and at the four quadrants with age but not for gender. The retinal sensitivity was highest in the IT quadrant and lowest in the SN quadrant for all age groups. The linear regression analysis revealed that there was a 0.019 dB, 0.016 dB, 0.022 dB, 0.029 dB and 0.029 dB per year age-related decline in mean macular sensitivity within the central 10° diameter in the SN, IN, IT and ST quadrants respectively. Conclusion Among normal healthy subjects, there was a linear decline in retinal light sensitivity with increasing age with the highest reduction in the superior nasal quadrant and lowest in the inferior temporal quadrant.

Original languageEnglish
Pages (from-to)266-272
Number of pages7
JournalJournal of Optometry
Volume8
Issue number4
DOIs
Publication statusPublished - 1 Oct 2015

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Nose
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Regression Analysis
Prospective Studies

Keywords

  • Age
  • Microperimetry
  • MP-1
  • Retinal sensitivity

ASJC Scopus subject areas

  • Optometry

Cite this

Macular retinal sensitivity using MP-1 in healthy Malaysian subjects of different ages. / Ismail, Siti Aishah; Malkeet Singh, Sharanjeet Kaur; Abdul Mutalib, Haliza; Ngah, Nor Fariza.

In: Journal of Optometry, Vol. 8, No. 4, 01.10.2015, p. 266-272.

Research output: Contribution to journalArticle

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