Low temperature capture of pseudorotaxanes

Nurul Izzaty Hassan, Vicente Del Amo, Ewen Calder, Douglas Philp

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Yields of a rotaxane can be improved by employing a two-step capture protocol. Cooling a solution of the linear and macrocyclic components required for the rotaxane increases the population of the target pseudorotaxane, which is then captured by a rapid capping reaction between an azide and PPh3. The resulting iminophosphorane rotaxane can then be manipulated synthetically at elevated temperatures.

Original languageEnglish
Pages (from-to)458-461
Number of pages4
JournalOrganic Letters
Volume13
Issue number3
DOIs
Publication statusPublished - 4 Feb 2011
Externally publishedYes

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Rotaxanes
cooling
Temperature
temperature
Azides
Health Services Needs and Demand
Cooling

ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Low temperature capture of pseudorotaxanes. / Hassan, Nurul Izzaty; Amo, Vicente Del; Calder, Ewen; Philp, Douglas.

In: Organic Letters, Vol. 13, No. 3, 04.02.2011, p. 458-461.

Research output: Contribution to journalArticle

Hassan, NI, Amo, VD, Calder, E & Philp, D 2011, 'Low temperature capture of pseudorotaxanes', Organic Letters, vol. 13, no. 3, pp. 458-461. https://doi.org/10.1021/ol1027915
Hassan, Nurul Izzaty ; Amo, Vicente Del ; Calder, Ewen ; Philp, Douglas. / Low temperature capture of pseudorotaxanes. In: Organic Letters. 2011 ; Vol. 13, No. 3. pp. 458-461.
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