Long term Tai Chi exercise reduced DNA damage and increased lymphocyte apoptosis and proliferation in older adults

Goon Jo Aan, A. H Noor Aini, M. Musalmah, Yasmin Anum Mohd Yusof, W. Z. Wan Ngah

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Effect of Tai Chi exercise on the level of DNA damage using the comet assay, lymphocyte viability and frequency of sister chromatid exchange (SCE) were determined in adults aged above 45. Tai Chi participants of 7 years (n=35), showed higher level of normal DNA and lower level of mild and severely damaged DNA as compared to the sedentary subjects (n=35). The former are suggested to have effective DNA repair mechanism as their frequency of SCE was markedly lower. Higher lymphocyte apoptosis and proliferation found in the Tai Chi participants also indicated that the exercise promotes renewal and regeneration of lymphocytes.

Original languageEnglish
Pages (from-to)319-324
Number of pages6
JournalMedical Journal of Malaysia
Volume63
Issue number4
Publication statusPublished - Oct 2008

Fingerprint

Tai Ji
DNA Damage
Sister Chromatid Exchange
Lymphocytes
Apoptosis
Comet Assay
DNA
DNA Repair
Regeneration

Keywords

  • Chromosome
  • DNA
  • Lymphocyte
  • Tai Chi

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Long term Tai Chi exercise reduced DNA damage and increased lymphocyte apoptosis and proliferation in older adults. / Jo Aan, Goon; Aini, A. H Noor; Musalmah, M.; Mohd Yusof, Yasmin Anum; Wan Ngah, W. Z.

In: Medical Journal of Malaysia, Vol. 63, No. 4, 10.2008, p. 319-324.

Research output: Contribution to journalArticle

Jo Aan, Goon ; Aini, A. H Noor ; Musalmah, M. ; Mohd Yusof, Yasmin Anum ; Wan Ngah, W. Z. / Long term Tai Chi exercise reduced DNA damage and increased lymphocyte apoptosis and proliferation in older adults. In: Medical Journal of Malaysia. 2008 ; Vol. 63, No. 4. pp. 319-324.
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