Lipid profile and antioxidant enzymes in Normal and stressed rat fed with Palm Olein

Eqbal M A Dauqan, Aminah Abdullah, Halimah Abdullah Sani

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Problem statement: The objective of the study was to evaluate the effect of Red Palm Olein (RPO) and Palm Olein (PO) on lipid profile and antioxidant enzyme in normal and stressed rat. Approach: Thirty six Sprague Dawley male rats which were randomly divided into six groups of 6 rats per group (tree normal groups and three stressed groups) were treated with 15% of RPO and PO for four weeks. Results: The results at 4 weeks of treatment showed a decline in Low Density Lipoprotein Cholesterol (LDL-C) level at RPO and PO for normal and stressed groups compared to the control group. The High Density Lipoprotein Cholesterol (HDL-C) level increased in RPO and PO of the normal and stressed groups. There was significant decreased (p≤0.05) in the TC in RPO normal group for 4 weeks of treatment compared to the control group while the TC in PO was within the normal range and increased in stressed group. After 4 weeks of treatment the study indicated that there was no significant (p≥0.05) effect on antioxidant enzyme (superoxide dismutase) in stressed rat liver but there was a significant decreased (p≤0.05) on catalase in stressed rat liver. Conclusion: These results could be due to the high content of vitamin E (tocopherols and tocotrienols) and β-carotene in red palm olein.

Original languageEnglish
Pages (from-to)1071-1078
Number of pages8
JournalAmerican Journal of Applied Sciences
Volume9
Issue number7
Publication statusPublished - 2012

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Antioxidants
Lipids
Enzymes
Tocotrienols
Control Groups
Tocopherols
Liver
Carotenoids
Vitamin E
Catalase
LDL Cholesterol
HDL Cholesterol
Superoxide Dismutase
Sprague Dawley Rats
Reference Values

Keywords

  • Atherosclerotic Heart Disease (AHD)
  • Glutamate Oxaloacetate Transaminase (GOT)
  • Glutamate Pyruvate Transaminase (GPT)
  • Low Density Lipoprotein Cholesterol (LDL-C)
  • Palm Olein (PO)
  • Red Palm Olein (RPO)
  • Total Cholesterol (TC)

ASJC Scopus subject areas

  • General

Cite this

Lipid profile and antioxidant enzymes in Normal and stressed rat fed with Palm Olein. / Dauqan, Eqbal M A; Abdullah, Aminah; Sani, Halimah Abdullah.

In: American Journal of Applied Sciences, Vol. 9, No. 7, 2012, p. 1071-1078.

Research output: Contribution to journalArticle

Dauqan, Eqbal M A ; Abdullah, Aminah ; Sani, Halimah Abdullah. / Lipid profile and antioxidant enzymes in Normal and stressed rat fed with Palm Olein. In: American Journal of Applied Sciences. 2012 ; Vol. 9, No. 7. pp. 1071-1078.
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