Linseed hydrogel-mediated green synthesis of silver nanoparticles for antimicrobial and wound-dressing applications

Muhammad Tahir Haseeb, Muhammad Ajaz Hussain, Khawar Abbas, Bahaa G M Youssif, Sajid Bashir, Soon Hong Yuk, Bukhari Syed Nasir Abbas

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Polysaccharides are being extensively employed for the synthesis of silver nanoparticles (Ag NPs) having diverse morphology and applications. Herein, we present a novel and green synthesis of Ag NPs without using any physical reaction conditions. Linseed hydrogel (LSH) was used as a template to reduce Ag+ to Ag0. AgNO3 (10, 20, and 30 mmol) solutions were mixed with LSH suspension in deionized water and exposed to diffused sunlight. Reaction was monitored by noting the change in the color of reaction mixture up to 10 h. Ag NPs showed characteristic ultraviolet-visible (UV/Vis) absorptions from 410 to 437 nm in the case of sunlight and 397–410 nm in the case of temperature study. Transmission electron microscopy images revealed the formation of spherical Ag NPs in the range of 10–35 nm. Face-centered cubic array of Ag NPs was confirmed by characteristic diffraction peaks in powder X-ray diffraction spectrum. Ag NPs were stored in LSH thin films, and UV/Vis spectra recorded after 6 months indicated that Ag NPs retained their texture over the storage period. Significant antimicrobial activity was observed when microbial cultures (bacteria and fungi) were exposed to the synthesized Ag NPs. Wound-healing studies revealed that Ag NP–impregnated LSH thin films could have potential applications as an antimicrobial dressing in wound management procedures.

Original languageEnglish
Pages (from-to)2845-2855
Number of pages11
JournalInternational Journal of Nanomedicine
Volume12
DOIs
Publication statusPublished - 6 Apr 2017
Externally publishedYes

Fingerprint

Flax
Hydrogel
Bandages
Silver
Hydrogels
Nanoparticles
Sunlight
Wounds and Injuries
Thin films
Deionized water
Polysaccharides
Fungi
Transmission Electron Microscopy
X-Ray Diffraction
Powders
Wound Healing
X ray powder diffraction
Suspensions
Bacteria
Color

Keywords

  • Antimicrobial studies
  • Green synthesis
  • Silver nanoparticles
  • Storage and stability
  • Wound dressing

ASJC Scopus subject areas

  • Bioengineering
  • Biophysics
  • Biomaterials
  • Drug Discovery
  • Organic Chemistry

Cite this

Haseeb, M. T., Hussain, M. A., Abbas, K., Youssif, B. G. M., Bashir, S., Yuk, S. H., & Syed Nasir Abbas, B. (2017). Linseed hydrogel-mediated green synthesis of silver nanoparticles for antimicrobial and wound-dressing applications. International Journal of Nanomedicine, 12, 2845-2855. https://doi.org/10.2147/IJN.S133971

Linseed hydrogel-mediated green synthesis of silver nanoparticles for antimicrobial and wound-dressing applications. / Haseeb, Muhammad Tahir; Hussain, Muhammad Ajaz; Abbas, Khawar; Youssif, Bahaa G M; Bashir, Sajid; Yuk, Soon Hong; Syed Nasir Abbas, Bukhari.

In: International Journal of Nanomedicine, Vol. 12, 06.04.2017, p. 2845-2855.

Research output: Contribution to journalArticle

Haseeb, MT, Hussain, MA, Abbas, K, Youssif, BGM, Bashir, S, Yuk, SH & Syed Nasir Abbas, B 2017, 'Linseed hydrogel-mediated green synthesis of silver nanoparticles for antimicrobial and wound-dressing applications', International Journal of Nanomedicine, vol. 12, pp. 2845-2855. https://doi.org/10.2147/IJN.S133971
Haseeb, Muhammad Tahir ; Hussain, Muhammad Ajaz ; Abbas, Khawar ; Youssif, Bahaa G M ; Bashir, Sajid ; Yuk, Soon Hong ; Syed Nasir Abbas, Bukhari. / Linseed hydrogel-mediated green synthesis of silver nanoparticles for antimicrobial and wound-dressing applications. In: International Journal of Nanomedicine. 2017 ; Vol. 12. pp. 2845-2855.
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