LC-MS analysis of phytocomponents in the methanol extract of piper sarmentosum leaves

Cutt Fazzlieanie Bactiar, Nur Azlina Mohd Fahami

Research output: Contribution to journalArticle

Abstract

Background: Piper sarmentosum is a cultivated plant that grows wildly in the tropical and subtropical region including in Malaysia. It has a wide usage in traditional medicine and have a variety of active chemical constituents. Aim: The aim of this study is to isolate and identify the active compounds from the methanol extracts of leaves of P. Sarmentosum. Methods and Materials: The fresh leaves of Piper sarmentosum were collected from the Ethnobotanic garden of Forest Research Institute Malaysia (FRIM) after being identified and confirmed by a plant taxonomist from Medicinal Plant Divison (Voucher specimen code no: FRI 45870). The methanolic extraction procedure were performed at FRIM labrotory. The extract was then sent to Research and Instrumentation Management Centre (CRIM) UKM for Liquid Chromatography Mass Spectrometry (LCMS) analysis. Results: Fifteen compounds were isolated from the fresh leaves of Piper sarmentosum. Six of these have been previously isolated from the roots and essential oil of this plant: (2) Naringenin, (3) Methyl piperate, (5) Beta-Asarone, (6) Brachyamide B, (8) Piperitol and (9)(10) Guineensine. (1)(12) Didymin, (4) Quercetin, (7) Amurensin (11) Hesperidin, and (15) Difucol are new for P. Sarmentosum (Piperaceae). Conclusions: From the result, it is evident that Piper sarmentosum contains various bioactive compounds. (1)(12) Didymin, (4) Quercetin, (7) Amurensin, (11) Hesperidin, and (15) Difucol are new natural compounds that have not been reported before.

Original languageEnglish
Pages (from-to)1071-1076
Number of pages6
JournalPharmacognosy Journal
Volume11
Issue number5
DOIs
Publication statusPublished - 1 Jan 2019

Fingerprint

Piper
Methanol
Malaysia
Hesperidin
Quercetin
Piperaceae
Traditional Medicine
Volatile Oils
Medicinal Plants
Liquid Chromatography
Mass Spectrometry
Research
didymin
Forests

Keywords

  • Flavanoids
  • Lignan
  • Liquid-chromatography mass-spectrometry (LC-MS) analysis
  • Naringine
  • Piper sarmentosum

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

Cite this

LC-MS analysis of phytocomponents in the methanol extract of piper sarmentosum leaves. / Bactiar, Cutt Fazzlieanie; Fahami, Nur Azlina Mohd.

In: Pharmacognosy Journal, Vol. 11, No. 5, 01.01.2019, p. 1071-1076.

Research output: Contribution to journalArticle

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