Late Temporal Lobe Extensive Osteoradionecrosis Post Radiation for Nasopharyngeal Carcinoma: Case Series

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Abstract

Osteoradionecrosis is one of the most serious complications of radiotherapy for nasopharyngeal carcinoma. We report three cases of osteoradionecrosis in temporal lobe who presented differently few years after completion of radiotherapy. Cranial magnetic resonance image showed lesions in temporal lobe either unilateral or bilateral with mass effect. One of the cases even showed disease progression few years after the initial diagnosis of osteoradionecrosis. Diagnosis of osteoradionecrosis for all three patients was confirmed by biopsy.

Original languageEnglish
JournalIndian Journal of Otolaryngology and Head and Neck Surgery
DOIs
Publication statusAccepted/In press - 22 Sep 2015

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Osteoradionecrosis
Temporal Lobe
Radiation
Radiotherapy
Disease Progression
Magnetic Resonance Spectroscopy
Biopsy
Nasopharyngeal carcinoma

Keywords

  • Complication
  • Nasopharyngeal carcinoma
  • Osteoradionecrosis
  • Radiotherapy

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Surgery

Cite this

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title = "Late Temporal Lobe Extensive Osteoradionecrosis Post Radiation for Nasopharyngeal Carcinoma: Case Series",
abstract = "Osteoradionecrosis is one of the most serious complications of radiotherapy for nasopharyngeal carcinoma. We report three cases of osteoradionecrosis in temporal lobe who presented differently few years after completion of radiotherapy. Cranial magnetic resonance image showed lesions in temporal lobe either unilateral or bilateral with mass effect. One of the cases even showed disease progression few years after the initial diagnosis of osteoradionecrosis. Diagnosis of osteoradionecrosis for all three patients was confirmed by biopsy.",
keywords = "Complication, Nasopharyngeal carcinoma, Osteoradionecrosis, Radiotherapy",
author = "Tang, {Chian Ling} and {Athi Kumar}, {Ramesh Kumar} and Toh, {Charng Jeng} and {Mohamed Mukari}, {Shahizon Azura} and Tan, {Geok Chin} and Gendeh, {Balwant Singh}",
year = "2015",
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journal = "Indian Journal of Otolaryngology and Head and Neck Surgery",
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T1 - Late Temporal Lobe Extensive Osteoradionecrosis Post Radiation for Nasopharyngeal Carcinoma

T2 - Case Series

AU - Tang, Chian Ling

AU - Athi Kumar, Ramesh Kumar

AU - Toh, Charng Jeng

AU - Mohamed Mukari, Shahizon Azura

AU - Tan, Geok Chin

AU - Gendeh, Balwant Singh

PY - 2015/9/22

Y1 - 2015/9/22

N2 - Osteoradionecrosis is one of the most serious complications of radiotherapy for nasopharyngeal carcinoma. We report three cases of osteoradionecrosis in temporal lobe who presented differently few years after completion of radiotherapy. Cranial magnetic resonance image showed lesions in temporal lobe either unilateral or bilateral with mass effect. One of the cases even showed disease progression few years after the initial diagnosis of osteoradionecrosis. Diagnosis of osteoradionecrosis for all three patients was confirmed by biopsy.

AB - Osteoradionecrosis is one of the most serious complications of radiotherapy for nasopharyngeal carcinoma. We report three cases of osteoradionecrosis in temporal lobe who presented differently few years after completion of radiotherapy. Cranial magnetic resonance image showed lesions in temporal lobe either unilateral or bilateral with mass effect. One of the cases even showed disease progression few years after the initial diagnosis of osteoradionecrosis. Diagnosis of osteoradionecrosis for all three patients was confirmed by biopsy.

KW - Complication

KW - Nasopharyngeal carcinoma

KW - Osteoradionecrosis

KW - Radiotherapy

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