Laryngeal histoplasmosis

An occupational hazard

Jian Woei Teoh, Faridah Hassan, Mohd. Razif Mohamad Yunus

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Isolated laryngeal histoplasmosis is a very rare entity. It has variable clinical presentations that might mimic both benign and malignant lesions, and is usually associated with pulmonary and other disseminated forms of histoplasmosis. Herein, we report a case of primary laryngeal histoplasmosis without the involvement of other systems in a 70-year-old Chinese man, who previously worked as a miner. He presented with a history of hoarseness for two months, with no other associated symptoms. Direct laryngoscopy revealed irregularity of the posterior onethird of both vocal folds. Histopathological examination revealed the presence of Histoplasma capsulatum on periodic acid-Schiff and Grocott's methenamine silver staining. The lesion resolved after one month of oral itraconazole treatment. However, the patient had to complete six months of antifungal treatment to prevent recurrence.

Original languageEnglish
JournalSingapore Medical Journal
Volume54
Issue number10
DOIs
Publication statusPublished - Oct 2013

Fingerprint

Histoplasmosis
Methenamine
Histoplasma
Hoarseness
Laryngoscopy
Silver Staining
Periodic Acid
Itraconazole
Vocal Cords
Recurrence
Lung
Therapeutics

Keywords

  • Histoplasmosis
  • Laryngeal infection
  • Leucoplakia

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Laryngeal histoplasmosis : An occupational hazard. / Teoh, Jian Woei; Hassan, Faridah; Mohamad Yunus, Mohd. Razif.

In: Singapore Medical Journal, Vol. 54, No. 10, 10.2013.

Research output: Contribution to journalArticle

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