Label-free bioparticles detection using Lab-on-Chip

Mohammadmahdi Vakilian, Burhanuddin Yeop Majlis

Research output: Contribution to journalArticle

Abstract

Lab-on-Chip (LOC) is a miniaturized device that is able to perform single or multiple laboratory operations on a single chip. This paper intends to study, explore and transform the laboratory-based bioparticles detection technique to part of LOC device. The combination of MEMS capacitive sensor and microfluidics is expected to develop and use as a LOC device to detect the E.coli bacteria in a water-based medium. In this research, the interdigitated electrodes (IDEs) were applied as the capacitive sensor due to their low cost, ease of fabrication process and excellent sensitivity. The capacitive sensor LOC was designed and simulated using the MEMS module in COMSOL Multiphysics. The effect of the number of bacteria on capacitance change was also discussed. The simulation results showed that by increasing the number of bacteria, the capacitance decreased.

Original languageEnglish
Pages (from-to)43747-43751
Number of pages5
JournalInternational Journal of Applied Engineering Research
Volume10
Issue number23
Publication statusPublished - 1 Dec 2015

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Capacitive sensors
Labels
Lab-on-a-chip
Bacteria
MEMS
Capacitance
Microfluidics
Escherichia coli
Fabrication
Electrodes
Costs
Water

Keywords

  • Bioparticle
  • Interdigitated electrodes
  • Lab-on-Chip
  • Label-free detection
  • Sensor

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Label-free bioparticles detection using Lab-on-Chip. / Vakilian, Mohammadmahdi; Yeop Majlis, Burhanuddin.

In: International Journal of Applied Engineering Research, Vol. 10, No. 23, 01.12.2015, p. 43747-43751.

Research output: Contribution to journalArticle

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